5-甲基水杨酸
5-甲基水杨酸用途
5-甲基水杨酸名称
[ CAS 号 ]:
89-56-5
[ 中文名 ]:
5-甲基水杨酸
[ 英文名 ]:
5-Methylsalicylic acid
[中文别名 ]:
[英文别名 ]:
- 2-Hydroxy-5-methylbenzoic acid
- MFCD00002461
- 5-Methyl Salicylic Acid
- Benzoic acid, 2-hydroxy-5-methyl-
- 5-methylsalicylic acid
- EINECS 201-918-6
5-甲基水杨酸生物活性
5-甲基水杨酸物理化学性质
[ 密度 ]:
1.3±0.1 g/cm3
[ 沸点 ]:
299.8±28.0 °C at 760 mmHg
[ 熔点 ]:
163-165 °C(lit.)
[ 分子式 ]:
C8H8O3
[ 分子量 ]:
152.15
[ 闪点 ]:
149.3±20.5 °C
[ 精确质量 ]:
152.047348
[ PSA ]:
57.53000
[ LogP ]:
2.52
[ 外观性状 ]:
无气味的白色晶体
[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C
[ 折射率 ]:
1.600
[ 储存条件 ]:
室温,干燥
5-甲基水杨酸MSDS
5-甲基水杨酸毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GP3920200
- CHEMICAL NAME :
- 2,5-Cresotic acid
- CAS REGISTRY NUMBER :
- 89-56-5
- BEILSTEIN REFERENCE NO. :
- 1909076
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C8-H8-O3
- MOLECULAR WEIGHT :
- 152.16
- WISWESSER LINE NOTATION :
- QVR BQ E1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Behavioral - analgesia
- REFERENCE :
- APSXAS Acta Pharmaceutica Suecica. (Apotekarsocieteten-Farmacevtiska Foereningen, Box 1136, S-111, 81 Stockholm, Sweden) V.1- 1964- Volume(issue)/page/year: 7,289,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 196,478,1976
5-甲基水杨酸安全信息
[ 符号 ]:
GHS07
[ 信号词 ]:
Warning
[ 危害声明 ]:
H302-H315-H319-H335
[ 警示性声明 ]:
P261-P305 + P351 + P338
[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves
[ 危害码 (欧洲) ]:
Xi:Irritant
[ 风险声明 (欧洲) ]:
R36/37/38
[ 安全声明 (欧洲) ]:
S26-S36/39-S22-S36
[ 危险品运输编码 ]:
NONH for all modes of transport
[ WGK德国 ]:
3
[ RTECS号 ]:
GP3920200
[ 海关编码 ]:
2942000000
5-甲基水杨酸合成路线
5-甲基水杨酸上下游产品
5-甲基水杨酸上游产品
5-甲基水杨酸下游产品
5-甲基水杨酸海关
[ 海关编码 ]: 2918290000
[ 中文概述 ]:
2918290000 其他含酚基但不含其他含氧基羧酸及其酸酐、酰卤化物、过氧化物和过氧酸及它们的衍生物。监管条件:AB(入境货物通关单,出境货物通关单)。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单
[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验
[ Summary ]:
HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%
5-甲基水杨酸文献
J. Med. Chem. 54 , 591-602, (2011)
Fragment-based lead design (FBLD) has been used to identify new metal-binding groups for metalloenzyme inhibitors. When screened at 1 mM, a chelator fragment library (CFL-1.1) of 96 compounds produced...
Radiation metabolomics. 1. Identification of minimally invasive urine biomarkers for gamma-radiation exposure in mice.Radiat. Res. 170(1) , 1-14, (2008)
Gamma-radiation exposure has both short- and long-term adverse health effects. The threat of modern terrorism places human populations at risk for radiological exposures, yet current medical counterme...
Specificity data of the salicylate assay by fluorescent polarization immunoassay.J. Anal. Toxicol. 13(6) , 358-60, (1989)
We studied the recently developed Abbott Laboratories fluorescent polarization immunoassay (FPIA) for salicylates in serum. The cross-reactivity test of the assay was performed with 20 substances that...
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