15854-11-2

15854-11-2结构式

常用中文名：2-氨基-4-(4-甲氧基苯基)-3-噻吩羧酸乙酯
常用英文名：Ethyl 2-amino-4-(4-methoxyphenyl)-3-thiophenecarboxylate
CAS号：15854-11-2
分子式：C₁₄H₁₅NO₃S
分子量：277.33900
发布时间：2018-12-22 16:05:33
更新时间：2024-01-02 18:08:11

中文名	2-氨基-4-(4-甲氧基苯基)-3-噻吩羧酸乙酯
英文名	ethyl 2-amino-4-(4-methoxyphenyl)thiophene-3-carboxylate
中文别名	2-氨基-4-(甲氧基苯基)噻吩-3-羧酸乙酯
英文别名	ethyl 2-amino-4-(4-methoxyphenyl)-3-thiophenecarboxylate 2-amino-3-carbethoxy-4-(4-methoxyphenyl)thiophene ethyl 2-amino-4-(4-methoxyphenyl)-thiophene-3-carboxylate 2-amino-4-(4-methoxy-phenyl)-thiophene-3-carboxylic acid ethyl ester F0745-0325 MFCD01917484

密度	1.233g/cm3
沸点	424.2ºC at 760mmHg
熔点	74ºC
分子式	C₁₄H₁₅NO₃S
分子量	277.33900
闪点	210.4ºC
精确质量	277.07700
PSA	89.79000
LogP	3.76380
蒸汽压	2.1E-07mmHg at 25°C
折射率	1.596

Name:	Ethyl 2-amino-4-(4-methoxyphenyl)-3-thiophenecarboxylate Material Safety Data Sheet
Synonym:	None Known
CAS:	15854-11-2

Section 1 - Chemical Product MSDS Name:Ethyl 2-amino-4-(4-methoxyphenyl)-3-thiophenecarboxylate Material Safety Data Sheet
Synonym:None Known

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
15854-11-2	Ethyl 2-amino-4-(4-methoxyphenyl)-3-th	97+	unlisted

Hazard Symbols: XI
Risk Phrases: 36/37/38

Section 3 - HAZARDS IDENTIFICATION

EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation. May cause chemical conjunctivitis.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.

Section 7 - HANDLING and STORAGE
Handling:
Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Wash clothing before reuse.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 15854-11-2: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: yellow
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 74-78 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C14H15NO3S
Molecular Weight: 277.34

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Dust generation.
Incompatibilities with Other Materials:
Oxidizing agents, acids, acid chlorides.
Hazardous Decomposition Products:
Carbon monoxide, oxides of nitrogen, oxides of sulfur, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 15854-11-2 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Ethyl 2-amino-4-(4-methoxyphenyl)-3-thiophenecarboxylate - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 22 Do not breathe dust.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
WGK (Water Danger/Protection)
CAS# 15854-11-2: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 15854-11-2 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 15854-11-2 is not listed on the TSCA inventory.
It is for research and development use only.

SECTION 16 - ADDITIONAL INFORMATION
N/A

危害码 (欧洲)	Xi: Irritant;
风险声明 (欧洲)	36
安全声明 (欧洲)	26
海关编码	2934999090

105-56-6

100-06-1

~46%

15854-11-2

文献：Synlett, , # 16 p. 2559 - 2564

123-11-5

105-56-6

~1%

15854-11-2

文献：WO2008/128072 A2, ; Page/Page column 37 ;

110-91-8

17463-82-0

15854-11-2

文献：US2003/73733 A1, ; US 20030073733 A1

17463-82-0

15854-11-2

文献：Synthetic Communications, , vol. 37, # 23 p. 4273 - 4279

上游产品 5
105-56-6 100-06-1 123-11-5 110-91-8
17463-82-0
下游产品 0

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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