965-90-2

• 常用中文名：乙基雌烯醇
• 常用英文名：Ethylestrenol
• CAS号：965-90-2
• 分子式：C₂₀H₃₂O
• 分子量：288.46700
• 发布时间：2018-08-15 10:36:07
• 更新时间：2024-01-08 10:12:22
• 【用途一】
  用作医药中间体

名称

• 中文名: 乙基雌烯醇
• 英文名: ethylestrenol
• 中文别名: 乙雌烯醇
• 英文别名: orgabolin; Orgaboral; ETHYLESTRENOL; durabolin-o; maxibolin; duraboral; org-483; MFCD00198958; EINECS 213-523-6; maxibalin; orabolin; ethylnandrol

物化性质

• 密度: 1.04 g/cm3
• 沸点: 401.4ºC at 760 mmHg
• 熔点: 76-78ºC
• 分子式: C₂₀H₃₂O
• 分子量: 288.46700
• 闪点: 167.4ºC
• 精确质量: 288.24500
• PSA: 20.23000
• LogP: 5.09030
• 折射率: 1.547

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : RC8961100 CHEMICAL NAME : 19-Nor-17-alpha-pregn-4-en-17-ol CAS REGISTRY NUMBER : 965-90-2 LAST UPDATED : 199103 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C20-H32-O MOLECULAR WEIGHT : 288.52 WISWESSER LINE NOTATION : L E5 B666 MUTJ E1 FQ F2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >666700 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,113,1982 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 1 gm/kg SEX/DURATION : female 2-6 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Fertility - abortion REFERENCE : FESTAS Fertility and Sterility. (American Fertility Soc., 608 13th Ave. S, Birmingham, AL 35282) V.1- 1950- Volume(issue)/page/year: 22,735,1971 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 1 gm/kg SEX/DURATION : female 15-19 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Newborn - stillbirth REFERENCE : FESTAS Fertility and Sterility. (American Fertility Soc., 608 13th Ave. S, Birmingham, AL 35282) V.1- 1950- Volume(issue)/page/year: 22,735,1971 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 20 mg/kg SEX/DURATION : female 17-20 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - urogenital system REFERENCE : ECJPAE Endocrinologia Japonica. (Japan Pub. Trading Co., Ltd., POB 5030, Tokyo International, Tokyo, Japan) V.1- 1954- Volume(issue)/page/year: 24,77,1977 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 15 mg/kg SEX/DURATION : male 15 day(s) pre-mating TOXIC EFFECTS : Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands REFERENCE : IJMRAQ Indian Journal of Medical Research. (Indian Council of Medical Research, Ansari Nagar, New Delhi 110 029, India) V.1- 1913- Volume(issue)/page/year: 59,768,1971 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 28 mg/kg SEX/DURATION : female 14 day(s) pre-mating TOXIC EFFECTS : Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Maternal Effects - uterus, cervix, vagina Reproductive - Fertility - other measures of fertility REFERENCE : CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 5,489,1972

安全

• 危险品运输编码: UN 3249
• 包装等级: III
• 危险类别: 6.1(b)

合成路线

3646-30-8 ~% 965-90-2

文献：Chemistry and Industry (London, United Kingdom), , p. 905

3646-28-4 ~% 965-90-2

文献：Chemistry and Industry (London, United Kingdom), , p. 905

3646-28-4 811-49-4 ~% 965-90-2

文献：Chemistry and Industry (London, United Kingdom), , p. 905

上下游产品

上游产品  3
3646-30-8 3646-28-4 811-49-4
下游产品  0