135632-53-0

• 常用中文名：4-Boc-氨甲基哌啶
• 常用英文名：tert-Butyl (piperidin-4-ylmethyl)carbamate
• CAS号：135632-53-0
• 分子式：C₁₁H₂₂N₂O₂
• 分子量：214.305
• 发布时间：2018-03-15 08:00:00
• 更新时间：2024-01-02 12:04:47
• 下载msds

名称

• 中文名: 4-(Boc-氨甲基)哌啶
• 英文名: 4-(Boc-aminomethyl)piperidine
• 中文别名: 4-Boc-氨甲基哌啶
• 英文别名: 2-Methyl-2-propanyl (4-piperidinylmethyl)carbamate; Carbamic acid, N-(4-piperidinylmethyl)-, 1,1-dimethylethyl ester; 4-(tert-Butoxycarbonylaminomethyl)piperidine; tert-Butyl (piperidin-4-ylmethyl)carbamate; 4-(Boc-Aminomethyl)Piperidine; tert-butyl N-(piperidin-4-ylmethyl)carbamate; MFCD01631214

物化性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 321.8±15.0 °C at 760 mmHg
• 熔点: 106-108ºC
• 分子式: C₁₁H₂₂N₂O₂
• 分子量: 214.305
• 闪点: 148.4±20.4 °C
• 精确质量: 214.168121
• PSA: 50.36000
• LogP: 1.59
• 外观性状: 白色固体
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.458
• 储存条件: Refrigerated.

MSDS

Name: tert-Butyl N-(4-piperidinylmethyl)carbamate 97% Material Safety Data Sheet Synonym: CAS: 135632-53-0 Section 1 - Chemical Product MSDS Name:tert-Butyl N-(4-piperidinylmethyl)carbamate 97% Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 135632-53-0 tert-Butyl N-(4-piperidinylmethyl)carb 97% unlisted Hazard Symbols: C Risk Phrases: 34 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Causes burns. Potential Health Effects Eye: Causes eye burns. Skin: Causes skin burns. Ingestion: Causes gastrointestinal tract burns. Inhalation: Causes chemical burns to the respiratory tract. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Do not induce vomiting. Get medical aid immediately. Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use foam, dry chemical, or carbon dioxide. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood. Storage: Store in a cool, dry place. Store in a tightly closed container. Corrosives area. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 135632-53-0: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 153 - 154 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Not available. Solubility in water: Specific Gravity/Density: Molecular Formula: C11H22N2O2 Molecular Weight: 214 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Oxidizing agents, acids, acid chlorides. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, acrid smoke and fumes, ammonia. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 135632-53-0 unlisted. LD50/LC50: Not available. Carcinogenicity: tert-Butyl N-(4-piperidinylmethyl)carbamate - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: AMINES, SOLID, CORROSIVE, N.O.S.* Hazard Class: 8 UN Number: 3259 Packing Group: III IMO Shipping Name: AMINES, SOLID, CORROSIVE, N.O.S. Hazard Class: 8 UN Number: 3259 Packing Group: III RID/ADR Shipping Name: AMINES, SOLID, CORROSIVE, N.O.S. Hazard Class: 8 UN Number: 3259 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: C Risk Phrases: R 34 Causes burns. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 135632-53-0: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 135632-53-0 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 135632-53-0 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): C:Corrosive
• 风险声明 (欧洲): R34
• 安全声明 (欧洲): S26-S36/37/39-S45
• 危险品运输编码: UN3259
• 海关编码: 2933399090

合成路线

7144-05-0 49761-82-2 ~68% 135632-53-0

文献：Yen, Chi-Feng; Hu, Cheng-Kung; Chou, Ming-Chen; Tseng, Chen-Tso; Wu, Chien-Huang; Huang, Ying-Huey; Chen, Shu-Jen; King, Chi-Hsin Richard Patent: US2006/281712 A1, 2006 ; Location in patent: Page/Page column 108-109 ; US 20060281712 A1

24424-99-5 7144-05-0 ~% 135632-53-0

文献：US5374731 A1, ;

上下游产品

上游产品  3
7144-05-0 49761-82-2 24424-99-5
下游产品  2
132740-52-4 392691-05-3

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%