918431-93-3

• 常用中文名：4-氰基-4-氟-1-哌啶羧酸 1,1-二甲基乙酯
• 常用英文名：tert-butyl 4-cyano-4-fluoropiperidine-1-carboxylate
• CAS号：918431-93-3
• 分子式：C₁₁H₁₇FN₂O₂
• 分子量：228.26300
• 发布时间：2018-12-27 19:32:38
• 更新时间：2024-01-20 23:36:56

名称

• 中文名: 4-氰基-4-氟-1-哌啶羧酸 1,1-二甲基乙酯
• 英文名: tert-butyl 4-cyano-4-fluoropiperidine-1-carboxylate
• 英文别名: 1-Piperidinecarboxylic acid,4-cyano-4-fluoro-,1,1-dimethylethyl ester; 1-t-butoxycarbonyl-4-cyano-4-fluoropiperidine; 4-cyano-4-fluoro-piperidine-1-carboxylic acid tert-butyl ester; 1-Boc-4-Cyano-4-fluoropiperidine

物化性质

• 分子式: C₁₁H₁₇FN₂O₂
• 分子量: 228.26300
• 精确质量: 228.12700
• PSA: 53.33000
• LogP: 2.18708

合成路线

918431-92-2 ~% 918431-93-3

文献：Shipe, William D.; Barrow, James C.; Yang, Zhi-Qiang; Lindsley, Craig W.; Yang, F. Vivien; Schlegel, Kelly-Ann S.; Shu, Youheng; Rittle, Kenneth E.; Bock, Mark G.; Hartman, George D.; Tang, Cuyue; Ballard, Jeanine E.; Kuo, Yuhsin; Adarayan, Emily D.; Prueksaritanont, Thomayant; Zrada, Matthew M.; Uebele, Victor N.; Nuss, Cindy E.; Connolly, Thomas M.; Doran, Scott M.; Fox, Steven V.; Kraus, Richard L.; Marino, Michael J.; Graufelds, Valerie Kuzmick; Vargas, Hugo M.; Bunting, Patricia B.; Hasbun-Manning, Martha; Evans, Rose M.; Koblan, Kenneth S.; Renger, John J. Journal of Medicinal Chemistry, 2008 , vol. 51, # 13 p. 3692 - 3695

91419-52-2 ~% 918431-93-3

文献：Verniest, Guido; Piron, Karel; Van Hende, Eva; Thuring, Jan Willem; MacDonald, Gregor; Deroose, Frederik; De Kimpe, Norbert Organic and Biomolecular Chemistry, 2010 , vol. 8, # 11 p. 2509 - 2512