7005-53-0

• 常用中文名：5-氨基二苯并环庚烷
• 常用英文名：5H-Dibenzo[a,d]cyclohepten-5-amine,10,11-dihydro-
• CAS号：7005-53-0
• 分子式：C₁₅H₁₅N
• 分子量：209.28600
• 发布时间：2018-04-11 08:00:00
• 更新时间：2024-01-09 11:54:28

名称

• 中文名: 5-氨基二苯并环庚烷
• 英文名: 6,11-dihydro-5H-dibenzo[1,2-a:1',2'-e][7]annulen-11-amine
• 英文别名: 5-amino-10,11-dihydro-5H-dibenzo<a,c>cycloheptene; 5H-Dibenzo(a,d)cycloheptene-5-amine,10,11-dihydro; 10,11-Dihydro-5H-dibenzol(a,d)cyclohepten-5-amine; 10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-amine; EINECS 230-280-1; 10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylamine; 5-amino-10,11-dihydro-5H-dibenzo<a,d>cycloheptane; 5-amino-10,11-dihydro-5H-dibenzo<a,d>cycloheptene; 10,11-dihydro-5h-dibenzo[a,d][7]annulen-5-amine; 10,11-dihydrodibenzo<a,d>cycloheptene-5-amine

物化性质

• 密度: 1.093g/cm3
• 沸点: 328.3ºC at 760 mmHg
• 分子式: C₁₅H₁₅N
• 分子量: 209.28600
• 闪点: 159.4ºC
• 精确质量: 209.12000
• PSA: 26.02000
• LogP: 3.53360
• 折射率: 1.612

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : HO7645000 CHEMICAL NAME : 5H-Dibenzo(a,d)cycloheptene-5-amine, 10,11-dihydro- CAS REGISTRY NUMBER : 7005-53-0 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C15-H15-N MOLECULAR WEIGHT : 209.31 WISWESSER LINE NOTATION : L C676&T&J BZ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 56 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02171

合成路线

59631-14-0 ~21% 7005-53-0

文献：Teodori, Elisabetta; Dei, Silvia; Quidu, Patricia; Budriesi, Roberta; Chiarini, Alberto; Garnier-Suillerot, Arlette; Gualtieri, Fulvio; Manetti, Dina; Romanelli, Maria Novella; Scapecchi, Serena Journal of Medicinal Chemistry, 1999 , vol. 42, # 10 p. 1687 - 1697

1210-33-9 ~% 7005-53-0

文献：Teodori, Elisabetta; Dei, Silvia; Quidu, Patricia; Budriesi, Roberta; Chiarini, Alberto; Garnier-Suillerot, Arlette; Gualtieri, Fulvio; Manetti, Dina; Romanelli, Maria Novella; Scapecchi, Serena Journal of Medicinal Chemistry, 1999 , vol. 42, # 10 p. 1687 - 1697

4985-15-3 ~% 108-01-0 7005-53-0

文献：Albert Pharmazie, 1984 , vol. 39, # 8 p. 548 - 550

1785-74-6 ~94% 7005-53-0

文献：Dziadulewicz, Edward K.; Ritchie, Timothy J.; Hallett, Allan; Snell, Christopher R.; Davies, John W.; Wrigglesworth, Roger; Dunstan, Andrew R.; Bloomfield, Graham C.; Drake, Gillian S.; McIntyre, Peter; Brown, Michael C.; Burgess, Gillian M.; Lee, Wai; Davis, Clare; Yaqoob, Mohammed; Phagoo, Steve B.; Phillips, Elsa; Perkins, Martin N.; Campbell, Elizabeth A.; Davis, Andrew J.; Rang, Humphrey P. Journal of Medicinal Chemistry, 2002 , vol. 45, # 11 p. 2160 - 2172

1210-35-1 ~% 7005-53-0

文献：Dziadulewicz, Edward K.; Ritchie, Timothy J.; Hallett, Allan; Snell, Christopher R.; Davies, John W.; Wrigglesworth, Roger; Dunstan, Andrew R.; Bloomfield, Graham C.; Drake, Gillian S.; McIntyre, Peter; Brown, Michael C.; Burgess, Gillian M.; Lee, Wai; Davis, Clare; Yaqoob, Mohammed; Phagoo, Steve B.; Phillips, Elsa; Perkins, Martin N.; Campbell, Elizabeth A.; Davis, Andrew J.; Rang, Humphrey P. Journal of Medicinal Chemistry, 2002 , vol. 45, # 11 p. 2160 - 2172

上下游产品

上游产品  5
1785-74-6 59631-14-0 1210-35-1 1210-33-9
4985-15-3
下游产品  1
62371-00-0