26049-68-3

• 常用中文名：Thiazole,2-hydrazinyl-4-(5-nitro-2-furanyl)-
• 常用英文名：Thiazole,2-hydrazinyl-4-(5-nitro-2-furanyl)-
• CAS号：26049-68-3
• 分子式：C₇H₆N₄O₃S
• 分子量：226.21300
• 发布时间：2017-08-04 00:27:28
• 更新时间：2024-01-10 08:54:51

名称

• 英文名: [4-(5-nitrofuran-2-yl)-1,3-thiazol-2-yl]hydrazine
• 英文别名: 2-Hydrazino-4-(5-nitro-2-furanyl)thiazole; 2-Hydrazino-4-(5-nitro-2-furyl)thiazole; 2-hydrazino-4-(5-nitrofuran-2-yl)-1,3-thiazole; 2-Hydrazino-4-<5-nitro-2-furyl>-thiazol; Thiazole,2-hydrazino-4-(5-nitro-2-furyl); 2-hydrazino-4-(5-nitro-furan-2-yl)-thiazole

物化性质

• 密度: 1.631g/cm3
• 沸点: 445.5ºC at 760 mmHg
• 分子式: C₇H₆N₄O₃S
• 分子量: 226.21300
• 闪点: 223.3ºC
• 精确质量: 226.01600
• PSA: 141.37000
• LogP: 2.24230
• 蒸汽压: 3.92E-08mmHg at 25°C
• 折射率: 1.718

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : XJ4900000 CHEMICAL NAME : Thiazole, 2-hydrazino-4-(5-nitro-2-furyl)- CAS REGISTRY NUMBER : 26049-68-3 LAST UPDATED : 199706 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C7-H6-N4-O3-S MOLECULAR WEIGHT : 226.23 WISWESSER LINE NOTATION : T5OJ BNW E- ET5N CSJ BMZ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 14 gm/kg/44W-C TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Lungs, Thorax, or Respiration - tumors TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 38 gm/kg/46W-C TOXIC EFFECTS : Tumorigenic - neoplastic by RTECS criteria Gastrointestinal - tumors Blood - leukemia TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 21 gm/kg/46W-C TOXIC EFFECTS : Tumorigenic - neoplastic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors Skin and Appendages - tumors TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 21 gm/kg/46W-C TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Skin and Appendages - tumors MUTATION DATA TYPE OF TEST : Phage inhibition capacity TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 100 ug/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 26,3,1974 *** REVIEWS *** TOXICOLOGY REVIEW CCSUDL Carcinogenesis--A Comprehensive Survey. (Raven Press, 1185 Ave. of the Americas, New York, NY 10036) V.1- 1976- Volume(issue)/page/year: 4,171,1978

合成路线

15057-21-3 ~% 26049-68-3

文献：Sherman,W.R.; Dickson,D.E. Journal of Organic Chemistry, 1962 , vol. 27, p. 1351 - 1355

18523-69-8 ~% 26049-68-3

文献：Sherman,W.R.; Dickson,D.E. Journal of Organic Chemistry, 1962 , vol. 27, p. 1351 - 1355

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