524955-09-7

• 常用中文名：[3-氯-4-(吡啶-2-甲氧基)苯基]甲胺
• 常用英文名：3-Chloro-4-[(pyridin-2-yl)methyloxy]aniline
• CAS号：524955-09-7
• 分子式：C₁₂H₁₁ClN₂O
• 分子量：234.682
• 发布时间：2018-12-26 19:02:49
• 更新时间：2024-01-05 11:04:10

名称

• 中文名: [3-氯-4-(吡啶-2-甲氧基)苯基]甲胺
• 英文名: 3-chloro-4-(pyridin-2-ylmethoxy)aniline
• 中文别名: 来那替尼中间体; 3-氯-4-[(吡啶-2-基)甲氧基]苯胺
• 英文别名: 3-CHLORO-4-((PYRIDIN-2-YL)METHOXY)ANILINE; 3-chloro-4-(2-pyridinylMethoxy)-BenzenaMine; Benzenamine, 3-chloro-4-(2-pyridinylmethoxy)-; 3-chloro-4-(pyridin-2-ylmethoxy)aniline; 3-chloro-4-(pyridine-2-ylmethoxy)aniline; 3-Chloro-4-(2-pyridinylmethoxy)aniline; 4-pyridin-2-yl-methoxy-3-chloroaniline; Benzenamine,3-chloro-4-(2-pyridinylmethoxy); 3-chloro-4-(pyridin-2-yl-methoxy)benzenamine; 3-Chloro-4-[(pyridin-2-yl)methyloxy]aniline

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 402.5±35.0 °C at 760 mmHg
• 熔点: 93 °C
• 分子式: C₁₂H₁₁ClN₂O
• 分子量: 234.682
• 闪点: 197.2±25.9 °C
• 精确质量: 234.055984
• PSA: 48.14000
• LogP: 1.74
• 外观性状: 固体;White to Light yellow to Light orange powder to crystal
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.630
• 储存条件: 室温，干燥

安全

• 海关编码: 2933399090

合成路线

179687-79-7 ~95% 524955-09-7

文献：WYETH Patent: US2006/270668 A1, 2006 ; Location in patent: Page/Page column 16-17 ;

3964-52-1 6959-47-3 ~94% 524955-09-7

文献：ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2006/64196 A1, 2006 ; Location in patent: Page/Page column 97 ; WO 2006/064196 A1

586-98-1 3964-52-1 ~32% 524955-09-7

文献：Gavai, Ashvinikumar V.; Han, Wen-Ching; Chen, Ping; Ruediger, Edward H.; Mastalerz, Harold; Fink, Brian E.; Norris, Derek J. Patent: US2005/197339 A1, 2005 ; Location in patent: Page/Page column 12 ; US 20050197339 A1

6959-47-3 ~% 524955-09-7

文献：Tianjin Hemay Bio-Tech Co., Ltd.; Zhang, Hesheng; Chen, Yingwei; He, Qingchao Patent: US2013/225579 A1, 2013 ;

350-30-1 ~% 524955-09-7

文献：KANIONUSA INC.; SHEN, Wang; ZHANG, Aimin; FAN, Junfa; ZHENG, Xiaoling Patent: WO2011/2523 A1, 2011 ; WO 2011/002523 A1

586-98-1 ~% 524955-09-7

文献：KANIONUSA INC.; SHEN, Wang; ZHANG, Aimin; FAN, Junfa; ZHENG, Xiaoling Patent: WO2011/2523 A1, 2011 ; WO 2011/002523 A1

619-08-9 ~% 524955-09-7

文献：Gu, Ning; Yang, Jiabin; Wang, Peng; Li, Lushen; Chen, Yang; Ji, Min Research on Chemical Intermediates, 2013 , vol. 39, # 7 p. 3105 - 3110

上下游产品

上游产品  6
179687-79-7 3964-52-1 6959-47-3 586-98-1
350-30-1 619-08-9
下游产品  3
698387-09-6 179687-79-7 848139-78-6

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%