- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：7-[4-(4-氟苯基)-6-异丙基-2-(N-甲基甲磺酰胺基)-5-嘧啶]-(3R)-叔丁基二甲硅氧基-5-氧代-(6E)-庚酸甲酯
- 纯度：95.0%
- 规格：
- 联系人：徐经理
- 联系电话：13311869306
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147118-38-5
147118-38-5结构式
- 常用中文名：7-[4-(4-氟苯基)-6-异丙基-2-(N-甲基甲磺酰胺基)-5-嘧啶]-(3R)-叔丁基二甲硅氧基-5-氧代-(6E)-庚酸甲酯
- 常用英文名：7-[4-fluorophenyl]-6-isopropyl)-2-(N-Methyl-N-MethylSulfonyl amino)pyrimidine-5-yl]-(3R)-3-(terbutyldimethylsilyloxy)-5-oxo-6E-heptane acid,Methyl ester
- CAS号：147118-38-5
- 分子式：C29H42FN3O6SSi
- 分子量：607.809
- 发布时间：2018-09-27 11:49:46
- 更新时间：2024-01-04 23:06:46
| 中文名 | 7-[4-(4-氟苯基)-6-异丙基-2-(N-甲基甲磺酰胺基)-5-嘧啶]-(3R)-叔丁基二甲硅氧基-5-氧代-(6E)-庚酸甲酯 |
|---|---|
| 英文名 | 7-[4-fluorophenyl]-6-isopropyl)-2-(N-Methyl-N-MethylSulfonyl amino)pyrimidine-5-yl]-(3R)-3-(terbutyldimethylsilyloxy)-5-oxo-6E-heptane acid,Methyl ester |
| 中文别名 |
瑞舒伐他汀钙中间体J8
7-[4-(4-氟苯基)-6-异丙基-2-(N-甲基甲磺酰胺基)-5-嘧啶]-3R-叔丁基二甲硅氧基-5-氧代-6E-庚酸甲酯 瑞舒伐他汀中间体H-1 |
| 英文别名 |
6-Heptenoic acid, 3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-oxo-, methyl ester, (3R,6E)-
Methyl 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidine-5-yl]-(3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-(6E)-heptanoate methyl (3R,6E)-3-{[tert-butyl(dimethyl)silyl]oxy}-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-5-oxohept-6-enoate Methyl (3R,6E)-3-{[tert-butyl(dimethyl)silyl]oxy}-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-5-oxohept-6-enoate methyl 7-[4-(4-fluorofenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)-pyrimidin-5-yl]-(3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-(E)-6-heptenate (3R,6E)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-oxo-6-heptenoic acid methyl ester methyl (3R,6E)-3-[[(1,1-dimethylethyl)dimethylsilyl]-oxo]-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidyl]-5-oxo-6-heptenoate methyl 7-[4-(4-flourophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-(3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-(E)-6-heptenoate methyl 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-(3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-(E)-6-heptenate 6-Heptenoic acid,3-[[(1,1-diMethylethyl)diMethylsilyl] oxy]-7-[4-(4-fluorophenyl)-6-(1-Methylethyl)-2-[Methyl (Methylsulfonyl)aMino]-5-pyriMidinyl]-5-oxo-,Methyl ester,(3R,6E) methyl 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-(3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-(E)-6-heptenoate Methyl (3R,6E)-3-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl}-5-oxo-6-heptenoate |
| 密度 | 1.2±0.1 g/cm3 |
|---|---|
| 沸点 | 679.1±65.0 °C at 760 mmHg |
| 分子式 | C29H42FN3O6SSi |
| 分子量 | 607.809 |
| 闪点 | 364.5±34.3 °C |
| 精确质量 | 607.254761 |
| PSA | 124.14000 |
| LogP | 5.42 |
| 蒸汽压 | 0.0±2.1 mmHg at 25°C |
| 折射率 | 1.528 |
|
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147118-38-5 |
| 文献：ORCHID CHEMICALS and PHARMACEUTICALS LIMITED Patent: WO2008/93205 A2, 2008 ; Location in patent: Page/Page column 7-8 ; |
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147118-38-5 |
| 文献：Bioorganic and Medicinal Chemistry, , vol. 5, # 2 p. 437 - 444 |
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147118-38-5 |
| 文献：Bioorganic and Medicinal Chemistry, , vol. 5, # 2 p. 437 - 444 |
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147118-38-5 |
| 文献：Bioorganic and Medicinal Chemistry, , vol. 5, # 2 p. 437 - 444 |
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147118-38-5 |
| 文献：Bioorganic and Medicinal Chemistry, , vol. 5, # 2 p. 437 - 444 |
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147118-38-5 |
| 文献：Bioorganic and Medicinal Chemistry, , vol. 5, # 2 p. 437 - 444 |
|
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147118-38-5 |
| 文献：Bioorganic and Medicinal Chemistry, , vol. 5, # 2 p. 437 - 444 |
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147118-38-5 |
| 文献：Bioorganic and Medicinal Chemistry, , vol. 5, # 2 p. 437 - 444 |
