949-36-0
949-36-0结构式
- 常用中文名：盐酸异丙肾上腺素
- 常用英文名：1,2-Benzenediol,4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-, hydrochloride (1:1)
- CAS号：949-36-0
- 分子式：C11H18ClNO3
- 分子量：247.71900
- 相关类别： 原料药 呼吸系统用药 平喘药
- 发布时间：2018-09-21 02:28:52
- 更新时间：2024-01-11 13:07:43
| 中文名 | 盐酸异丙肾上腺素 |
|---|---|
| 英文名 | isoproterenol hydrochloride |
| 英文别名 |
isoproterenol HCl
MFCD00012603 racemicisoprenalinehydrochloride Saventrine IV ISOPRENALINE HCL dl-isoprenalinehydrochloride dl-isadrinehydrochloride ISOPROPYLARTERENOL HYDROCHLORIDE vapo-iso asthpul isoprenaline EINECS 200-089-8 |
| 密度 | 1.199g/cm3 |
|---|---|
| 沸点 | 417.5ºC at 760mmHg |
| 熔点 | 165-175ºC (dec.)(lit.) |
| 分子式 | C11H18ClNO3 |
| 分子量 | 247.71900 |
| 闪点 | 179.7ºC |
| 精确质量 | 247.09800 |
| PSA | 72.72000 |
| LogP | 2.32210 |
Synonym:DL-N-Isopropylnoradrenaline hydrochlorid Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: None Listed. Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Hygroscopic (absorbs moisture from the air).Light sensitive. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Ingestion: The toxicological properties of this substance have not been fully investigated. May be harmful if swallowed. Inhalation: May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Use only in a chemical fume hood. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 949-36-0: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 175 deg C dec Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: in water: 1gr/3ml Specific Gravity/Density: Molecular Formula: C11H17NO3.HCl Molecular Weight: 247.72 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials, dust generation. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 949-36-0: DO1930000 LD50/LC50: CAS# 949-36-0: Inhalation, mouse: LC50 = 10 gm/m3; Oral, mouse: LD50 = 1260 mg/kg; Oral, rabbit: LD50 = 3070 mg/kg; Oral, rat: LD50 = >2 gm/kg. Carcinogenicity: DL-ISOPROTERENOL HYDROCHLORIDE - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 949-36-0: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 949-36-0 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 949-36-0 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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| 危害码 (欧洲) | Xi: Irritant; |
|---|---|
| 风险声明 (欧洲) | 36/37/38 |
| 安全声明 (欧洲) | 26-36 |
| WGK德国 | 2 |
| RTECS号 | DO1925000 |