75965-74-1

• 常用中文名：2-硝基-7-甲氧基萘并[2,1-B]呋喃
• 常用英文名：7-METHOXY-2-NITRONAPHTHO(2,1-b)FURAN
• CAS号：75965-74-1
• 分子式：C₁₃H₉NO₄
• 分子量：243.21500
• 相关类别： 分析化学 标准品 挥发性有机化合物(VOCs)
• 发布时间：2018-12-13 16:39:59
• 更新时间：2024-01-06 20:26:55

名称

• 中文名: 2-硝基-7-甲氧基萘并[2,1-B]呋喃
• 英文名: 7-methoxy-2-nitrobenzo[e][1]benzofuran
• 英文别名: methoxy-7 nitro-2 naphto<2,1-b>furane; 2-Nitro-7-methoxynaphtho(2,1-b)furan; 7-methoxy-2-nitronaphtho[2,1-b]furan; 5-nitrofuran; nitronaphthofuran (R-7000); nitro-2 methoxy-7 naphto<2,1-b>furanne; R 7000

物化性质

• 密度: 1.379g/cm3
• 沸点: 420ºC at 760 mmHg
• 分子式: C₁₃H₉NO₄
• 分子量: 243.21500
• 闪点: 207.8ºC
• 精确质量: 243.05300
• PSA: 68.19000
• LogP: 4.02600
• 折射率: 1.69
• 储存条件: 2-8°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : QL0840000 CHEMICAL NAME : Naphtho(2,1-b)furan, 7-methoxy-2-nitro- CAS REGISTRY NUMBER : 75965-74-1 LAST UPDATED : 199612 DATA ITEMS CITED : 19 MOLECULAR FORMULA : C13-H9-N-O4 MOLECULAR WEIGHT : 243.23 WISWESSER LINE NOTATION : T B566 EOJ DNW KO1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 210 mg/kg/91W-C TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 24 mg/kg/36W-I TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Tumorigenic - tumors at site of application TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 11967 ug/kg TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 20 mg/kg/10W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 360 mg/kg/12W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 10 mg/kg/5W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application TYPE OF TEST : Sperm Morphology MUTATION DATA TYPE OF TEST : Mutation test systems - not otherwise specified TEST SYSTEM : Bird - chicken Embryo DOSE/DURATION : 1 mg/L REFERENCE : AMACCQ Antimicrobial Agents and Chemotherapy. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.1- 1972- Volume(issue)/page/year: 23,328,1983

合成路线

563-70-2 50493-59-9 ~66% 75965-74-1

文献：Royer; Buisson European Journal of Medicinal Chemistry, 1980 , vol. 15, # 3 p. 275 - 278

55218-08-1 ~% 75965-74-1

文献：Royer; Buisson European Journal of Medicinal Chemistry, 1980 , vol. 15, # 3 p. 275 - 278

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