78798-08-0

• 常用中文名：Kijanimicin
• 常用英文名：Kijanimicin
• CAS号：78798-08-0
• 分子式：C₆₇H₁₀₀N₂O₂₄
• 分子量：1317.51
• 相关类别： 研究领域 感染
• 发布时间：2017-01-13 04:52:49
• 更新时间：2024-09-22 12:06:09
• Kijanimicin (Sch 25663) 是由 Actinomadura kijaniata SCC 1256 产生的抗生素 (antibiotic)。

名称

• 英文名: From Actinomadura Kijaniata
• 英文别名: kijanimicin

物化性质

• 密度: 1.35g/cm3
• 分子式: C₆₇H₁₀₀N₂O₂₄
• 分子量: 1317.51
• 精确质量: 1316.67000
• PSA: 350.43000
• LogP: 6.36800
• 折射率: 1.596

生物活性

• 描述: Kijanimicin (Sch 25663) 是由 Actinomadura kijaniata SCC 1256 产生的抗生素 (antibiotic)。
• 相关类别:
  研究领域 >> 感染
• 参考文献:

  [1]. J A Waitz, et al. Kijanimicin (Sch 25663), a novel antibiotic produced by Actinomadura kijaniata SCC 1256. Fermentation, isolation, characterization and biological properties. J Antibiot (Tokyo). 1981 Sep;34(9):1101-6.

  [2]. Waitz JA, et al. Kijanimicin (Sch 25663), a novel antibiotic produced by Actinomadura kijaniata SCC 1256. Fermentation, isolation, characterization and biological properties. J Antibiot (Tokyo). 1981 Sep;34(9):1101-6.

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : OB8650500 CHEMICAL NAME : Kijanimicin CAS REGISTRY NUMBER : 78798-08-0 LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C67-H100-N2-O24 MOLECULAR WEIGHT : 1317.69 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 125 mg/kg TOXIC EFFECTS : Gastrointestinal - peritonitis REFERENCE : TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 4,6,1984 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #33840 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 170 mg/kg TOXIC EFFECTS : Gastrointestinal - peritonitis REFERENCE : TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 4,6,1984 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #33840