3483-19-0

• 常用中文名：3-(4-methylphenyl)-1,2,35-oxadiazol-5-ol
• 常用英文名：3-(4-methylphenyl)-1,2,35-oxadiazol-5-ol
• CAS号：3483-19-0
• 分子式：C₉H₈N₂O₂
• 分子量：176.17200
• 发布时间：2017-02-09 19:42:51
• 更新时间：2024-01-13 14:56:55

名称

• 英文名: 3-(4-methylphenyl)oxadiazol-3-ium-5-olate
• 英文别名: Sydnone,3-p-tolyl; 3-p-tolyl-sydnone; N-tolyl-sydnone

物化性质

• 分子式: C₉H₈N₂O₂
• 分子量: 176.17200
• 精确质量: 176.05900
• PSA: 52.97000
• LogP: 1.40350

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : WU7694500 CHEMICAL NAME : Sydrone, 3-p-tolyl- CAS REGISTRY NUMBER : 3483-19-0 BEILSTEIN REFERENCE NO. : 3672154 LAST UPDATED : 199712 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C9-H8-N2-O2 MOLECULAR WEIGHT : 176.19 WISWESSER LINE NOTATION : T5NNOVJ AR D1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 753 mg/kg TOXIC EFFECTS : Autonomic Nervous System - smooth muscle relaxant (mechanism undefined, spasmolytic) Behavioral - anticonvulsant Behavioral - altered sleep time (including change in righting reflex) REFERENCE : ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. Volume(issue)/page/year: 14,369,1965

合成路线

52827-02-8 ~83% 3483-19-0

文献：Deshpande, Shreenivas R.; Vasantakumar Pai E-Journal of Chemistry, 2010 , vol. 7, # 1 p. 59 - 64

21911-69-3 ~90% 3483-19-0

文献：Azarifar, Davood; Ghasemnejad-Bosra, Hassan; Ghorbani-Vaghei, Ramin; Tajbaksh, Mahmood Heterocycles, 2006 , vol. 68, # 11 p. 2343 - 2347

21911-68-2 ~% 3483-19-0

文献：Nithinchandra; Kalluraya; Aamir; Shabaraya European Journal of Medicinal Chemistry, 2012 , vol. 54, p. 597 - 604

106-49-0 ~% 3483-19-0

文献：Azarifar, Davood; Bosra, Hassan Ghasemnejad; Zolfigol, Mohammad-Ali; Tajbaksh, Mahmood Heterocycles, 2006 , vol. 68, # 1 p. 175 - 181

上下游产品

上游产品  4
52827-02-8 21911-69-3 21911-68-2 106-49-0
下游产品  2
637-60-5 3682-73-3