593-74-8

• 常用中文名：二甲基汞
• 常用英文名：dimethylmercury
• CAS号：593-74-8
• 分子式：C₂H₆Hg
• 分子量：230.65900
• 相关类别： 有机原料 有机金属类化合物 有机铪、汞、银、铂等
• 发布时间：2018-02-22 08:00:00
• 更新时间：2024-01-02 12:00:59

• 2、用途

  用于制备三甲基镓。

名称

• 中文名: 二甲基汞
• 英文名: dimethylmercury
• 中文别名: 2-丙烯基-4,6-联苯甲酰间苯二酚醇; 甲基汞
• 英文别名: Dimethyl-quecksilber; MFCD00014845; Mercury,dimethyl; DIMETHYLMERCURY; methyl-Hg-methyl; diemthylmercury; dimethylmercure; EINECS 209-805-3; dimethyl-mercury; UNII-C60TQU15XY

物化性质

• 密度: 2.961 g/mL at 25ºC(lit.)
• 沸点: 93-94ºC(lit.)
• 熔点: -43ºC(lit.)
• 分子式: C₂H₆Hg
• 分子量: 230.65900
• 闪点: 42ºC
• 精确质量: 232.01800
• LogP: 1.16510
• 外观性状: 无色液体
• 折射率: n20/D 1.543(lit.)
• 储存条件: Flammables area
• 稳定性: Stable. Highly flammable. Incompatible with strong oxidizing agents.
• 水溶解性: insoluble H2O; soluble ether, alcohol [MER06]
• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:0

  3.氢键受体数量:0

  4.可旋转化学键数量:0

  5.互变异构体数量:无

  6.拓扑分子极性表面积0

  7.重原子数量:3

  8.表面电荷:0

  9.复杂度:2.8

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多: 物性数据： 1. 性状：无色挥发性易燃液体。味甜

  2. 密度（g/mL ,25/4℃）：3.1874

  3. 折射率（nD20）：1.54735

  4. 熔点（℃）：-43℃

  5. 沸点（ºC, 98.7kPa）：92℃

  6. 溶解性：易溶于乙醚、乙醇，不溶于水

MSDS

Name: Dimethylmercury 95% Material Safety Data Sheet Synonym: None CAS: 593-74-8 Section 1 - Chemical Product MSDS Name:Dimethylmercury 95% Material Safety Data Sheet Synonym:None Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 593-74-8 Dimethylmercury 95 209-805-3 Hazard Symbols: T+ F Risk Phrases: 11 33 39/27 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Highly flammable. Danger of cumulative effects. Very toxic : danger of very serious irreversible effects in contact with skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be fatal if absorbed through the skin. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. If absorbed, causes symptoms similar to those of inhalation. Effects may be delayed. May cause severe dermatitis and burns. Ingestion: May cause irritation of the digestive tract. May cause effects similar to those for inhalation exposure. Inhalation: Inhalation of fumes may cause metal fume fever, which is characterized by flu-like symptoms with metallic taste, fever, chills, cough, weakness, chest pain, muscle pain and increased white blood cell count. Systemic intoxication is cumulative and has been fatal. May produce numbness and tingling of the lips, hands, and feet (paresthesia) and ataxia (failure of muscular coordination). Exposure may produce speech disturbances, constriction of the visual fields, hearing impairment, and emotional disturbances. Severe intoxication may produce clonic seizures, (which may be irreversible), incontinence, spasticity, jerking of the limbs, head, and shoulders. Severe intoxication may produce emotional disturbances, hypersalivation, tearing, nausea, vomiting, and diarrhea or constipation. Chronic: Prolonged or repeated skin contact may cause dermatitis. Chronic inhalation and ingestion may cause effects similar to those of acute inhalation and ingestion. May cause fetal effects. Chronic exposure to mercury may cause permanent central nervous system damage, fatigue, weight loss, tremors, personality changes. Chronic ingestion may cause accumulation of mercury in body tissues. Chronic exposure to mercury vapors may produce weakness, fatigue, anorexia, loss of weight and gastrointestinal disturbances which is collectively referred to as asthenic-vegetative syndrome or micromercurialism. Chronic exposure to mercury compounds may produce immunologic glomerular disease. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed. Skin: Get medical aid immediately. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Discard contaminated clothing in a manner which limits further exposure. SPEEDY ACTION IS CRITICAL! Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Flammable liquid and vapor. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Containers may explode when heated. Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all sources of ignition. Provide ventilation. A vapor suppressing foam may be used to reduce vapors. Water spray may reduce vapor but may not prevent ignition in closed spaces. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Do not ingest or inhale. Use only in a chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use only under a chemical fume hood. Exposure Limits CAS# 593-74-8: United States OSHA: 0.4 mg/m3 Ceiling (listed under Mercury, alk compounds). Belgium - TWA: (listed as mercury, alkyl compounds): 0.01 mg/m3 V (as Hg) Belgium - STEL: (listed as mercury, alkyl compounds): 0.03 mg/m3 (as Hg) France - VME: (listed as mercury, alkyl compounds): 0.01 mg/m3 VM (as Hg) Germany: (listed as mercury, alkyl compounds): 0.01 mg/m3 VME (as Malaysia: (listed as mercury, alkyl compounds): 0.01 mg/m3 TWA (a Hg) Netherlands: (listed as mercury, alkyl compounds): 0.02 mg/m3 STE (as Hg) Netherlands: (listed as mercury, alkyl compounds): 0.01 mg/m3 MAC Hg) Spain: (listed as mercury, alkyl compounds): 0.01 mg/m3 VLA-ED (a Hg) Spain: (listed as mercury, alkyl compounds): 0.03 mg/m3 VLA-EC (a Hg) Personal Protective Equipment Eyes: Wear chemical splash goggles. Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear plastic-laminate glove (SilverShield) alone or in combination with other gloves. Clothing: Wear appropriate protective clothing to prevent skin exposure. Wear an impervious apron. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Liquid Color: colorless Odor: faint sweet odor pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: 93 - 94 deg C Freezing/Melting Point: -43 deg C Autoignition Temperature: Not available. Flash Point: 5 deg C ( 41.00 deg F) Explosion Limits, lower: Not available. Explosion Limits, upper: N/A Decomposition Temperature: Solubility in water: Specific Gravity/Density: 2.9610g/cm3 Molecular Formula: C2H6Hg Molecular Weight: 230.67 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable at room temperature in closed containers under normal storage and handling conditions. Conditions to Avoid: Incompatible materials, ignition sources, excess heat. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, toxic fumes of mercury. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 593-74-8: OW3010000 LD50/LC50: Not available. Carcinogenicity: Dimethylmercury - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: FLAMMABLE LIQUID, TOXIC, N.O.S.* Hazard Class: 3 (6.1) UN Number: 1992 Packing Group: I IMO Shipping Name: FLAMMABLE LIQUID, TOXIC, N.O.S. Hazard Class: 3.2 (6.1) UN Number: 1992 Packing Group: I RID/ADR Shipping Name: FLAMMABLE LIQUID, TOXIC, N.O.S. Hazard Class: 3 (6.1) UN Number: 1992 Packing group: I Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: T+ F Risk Phrases: R 11 Highly flammable. R 33 Danger of cumulative effects. R 39/27 Very toxic : danger of very serious irreversible effects in contact with skin. Safety Phrases: S 9 Keep container in a well-ventilated place. S 13 Keep away from food, drink and animal feeding stuffs. S 16 Keep away from sources of ignition - No smoking. S 28A After contact with skin, wash immediately with plenty of water. S 33 Take precautionary measures against static discharges. S 36 Wear suitable protective clothing. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 593-74-8: No information available. Canada CAS# 593-74-8 is listed on Canada's NDSL List. CAS# 593-74-8 is listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 593-74-8 is listed on the TSCA inventory. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

生态学数据: 三、生态学数据： 1、其它有害作用：该物质对环境可能有危害，对水体应给予特别注意。 CHEMICAL IDENTIFICATION RTECS NUMBER : OW3010000 CHEMICAL NAME : Mercury, dimethyl CAS REGISTRY NUMBER : 593-74-8 BEILSTEIN REFERENCE NO. : 3600205 LAST UPDATED : 199712 DATA ITEMS CITED : 32 MOLECULAR FORMULA : C2-H6-Hg MOLECULAR WEIGHT : 230.67 WISWESSER LINE NOTATION : 1-HG-1 HEALTH HAZARD DATA ACUTE TOXICITY DATA MUTATION DATA TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 40 mg/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 290,281,1993 *** REVIEWS *** ACGIH TLV-TWA 0.01 mg(Hg)/m3; STEL 0.03 mg/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 58,239,1993 IARC Cancer Review:Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 58,239,1993 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 0.001 ppm (0.01 mg(Hg)/m3) DTLWS* "Documentation of the Threshold Limit Values for Substances in Workroom Air," Supplements. For publisher information, see 85INA8. Volume(issue)/page/year: 3,22,1973 OSHA PEL (Gen Indu):8H TWA 0.01 mg(Hg)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.01 mg(Hg)/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.01 mg(Hg)/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.01 mg(Hg)/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 0.01 mg(Hg)/m3;STEL 0.03 mg(Hg)/m3;Skin JAN 1993 OEL-BELGIUM:TWA 0.01 mg(Hg)/m3;STEL 0.03 mg(Hg)/m3;Skin JAN 1993 OEL-DENMARK:TWA 0.01 mg(Hg)/m3;Skin JAN 1993 OEL-FINLAND:TWA 0.01 mg(Hg)/m3;Skin JAN 1993 OEL-FRANCE:TWA 0.01 mg(Hg)/m3;Skin JAN 1993 OEL-THE NETHERLANDS:TWA 0.01 mg(Hg)/m3;STEL 0.02 mg(Hg)/m3;Skin JAN 1993 OEL-THE PHILIPPINES:TWA 0.01 mg(Hg)/m3 JAN 1993 OEL-SWEDEN:TWA 0.01 mg(Hg)/m3;Skin JAN 1993 OEL-THAILAND:TWA 0.01 mg(Hg)/m3;STEL 0.04 mg(Hg)/m3 JAN 1993 OEL-TURKEY:TWA 0.01 mg(Hg)/m3;Skin JAN 1993 OEL-UNITED KINGDOM:TWA 0.01 mg(Hg)/m3;STEL 0.03 mg(Hg)/m3;Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

安全

• 危害码 (欧洲): T+,N
• 风险声明 (欧洲): R26/27/28
• 安全声明 (欧洲): S26-S36
• 危险品运输编码: UN 3383
• WGK德国: 3
• RTECS号: OW3010000
• 包装等级: II
• 危险类别: 3.1

合成路线

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制备

1、生产方法简介

由甲基溴化镁或甲基锂与氯化汞在四氢呋喃或乙醚中反应制得。