804518-03-4

• 常用中文名：Milveterol hydrochloride
• 常用英文名：Milveterol hydrochloride
• CAS号：804518-03-4
• 分子式：C₂₅H₃₀ClN₃O₄
• 分子量：471.97600
• 发布时间：2017-02-01 23:07:42
• 更新时间：2024-01-12 10:03:26
• Milveterol (GSK 159797) is a potent, selective long-acting β2 adrenoceptor agonist with pEC50 of 10.2 in cell-based assays, displays good β2/β1 selectivity (>300-fold).

名称

• 英文名: N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[2-[4-[[(2R)-2-hydroxy-2-phenylethyl]amino]phenyl]ethylamino]ethyl]phenyl]formamide,hydrochloride
• 英文别名: TD-3327; Milveterol HCl; Milveterol hydrochloride

物化性质

• 分子式: C₂₅H₃₀ClN₃O₄
• 分子量: 471.97600
• 精确质量: 471.19200
• PSA: 117.34000
• LogP: 4.88710

合成路线

804518-04-5 ~89% 804518-03-4

文献：GLAXO GROUP LIMITED Patent: WO2005/95328 A1, 2005 ; Location in patent: Page/Page column 28-29 ;

652990-07-3 ~71% 804518-03-4

文献：GLAXO GROUP LIMITED Patent: WO2005/95328 A1, 2005 ; Location in patent: Page/Page column 26 ;

652990-08-4 ~% 804518-03-4

文献：Caine, Darren M.; Paternoster, Ian L.; Sedehizadeh, Simon; Shapland, Peter D. P. Organic Process Research and Development, 2012 , vol. 16, # 3 p. 518 - 523

上下游产品

上游产品  3
804518-04-5 652990-07-3 652990-08-4
下游产品  0