81347-68-4

• 常用中文名：1-(3-Chloro-1-phenylpropoxy)-4-(trifluoromethyl)benzene
• 常用英文名：1-(3-Chloro-1-phenylpropoxy)-4-(trifluoromethyl)benzene
• CAS号：81347-68-4
• 分子式：C₁₆H₁₄ClF₃O
• 分子量：314.73000
• 发布时间：2016-05-07 11:16:15
• 更新时间：2024-01-28 21:46:56

名称

• 英文名: 1-(3-Chloro-1-phenylpropoxy)-4-(trifluoromethyl)benzene
• 英文别名: 3-phenyl-3-(o-methylphenoxy)propylamine hydrochloride; |A-(2-Methylphenoxy)benzenepropanamine Hydrochloride; (3R)-3-(2-methylphenoxy)-3-phenylpropan-1-amine,hydrochloride; 3-(p-trifluoromethylphenoxy)-3-phenylpropylamine oxalate; Desmethyl Atomoxetine Hydrochloride; 3-phenyl-3-(p-trifluoromethylphenoxy)propylchloride; 3-phenyl-3-(o-methoxyphenyl)propylamine hydrochloride; 1-chloro-3-phenyl-3-(4-trifluoromethylphenoxy)propane; 1-chloro-3-(4-trifluormethyl-phenoxy)-3-phenyl-propane; 1-phenyl-1-(4-trifluorophenoxy)-3-chloropropane; 3-phenyl-3-(p-trifluoromethylphenoxy)propylamine oxalate

物化性质

• 分子式: C₁₆H₁₄ClF₃O
• 分子量: 314.73000
• 精确质量: 314.06900
• PSA: 9.23000
• LogP: 5.45440

合成路线

402-45-9 18776-12-0 ~67% 81347-68-4

文献：HUMAN BIOMOLECULAR RESEARCH INSTITUTE Patent: WO2006/25920 A2, 2006 ; Location in patent: Page/Page column 147-148 ; WO 2006/025920 A2

21763-00-8 402-45-9 ~% 81347-68-4

文献：Silvestri, Romano; Artico, Marino; La Regina, Giuseppe; Di Pasquali, Alessandra; De Martino, Gabriella; D'Auria, Felicia Diodata; Nencioni, Lucia; Palamara, Anna Teresa Journal of Medicinal Chemistry, 2004 , vol. 47, # 16 p. 3924 - 3926

936-59-4 ~% 81347-68-4

文献：Silvestri, Romano; Artico, Marino; La Regina, Giuseppe; Di Pasquali, Alessandra; De Martino, Gabriella; D'Auria, Felicia Diodata; Nencioni, Lucia; Palamara, Anna Teresa Journal of Medicinal Chemistry, 2004 , vol. 47, # 16 p. 3924 - 3926

18776-12-0 ~% 81347-68-4

文献：Silvestri, Romano; Artico, Marino; La Regina, Giuseppe; Di Pasquali, Alessandra; De Martino, Gabriella; D'Auria, Felicia Diodata; Nencioni, Lucia; Palamara, Anna Teresa Journal of Medicinal Chemistry, 2004 , vol. 47, # 16 p. 3924 - 3926

104-52-9 ~% 81347-68-4

文献：Andersen, Jacob; Stuhr-Hansen, Nicolai; Zachariassen, Linda Gronborg; Koldso, Heidi; Schiott, Birgit; Stromgaard, Kristian; Kristensen, Anders S. Molecular Pharmacology, 2014 , vol. 85, # 5 p. 703 - 714