462-73-7

• 常用中文名：1-氯-4-氟丁烷
• 常用英文名：1-chloro-4-fluorobutane
• CAS号：462-73-7
• 分子式：C₄H₈ClF
• 分子量：110.55800
• 发布时间：2016-05-24 13:30:51
• 更新时间：2024-01-24 17:06:25

名称

• 中文名: 1-氯-4-氟丁烷
• 英文名: 1-chloro-4-fluorobutane
• 中文别名: 1-氟-4-氯丁烷
• 英文别名: 4-Fluorobutyl chloride; 1-fluoro-4-chlorobutane; 1-Chlor-4-fluorbutan; 1-chloro-4-fluoro-butane; BUTANE,1-CHLORO-4-FLUORO

物化性质

• 密度: 0.992g/cm3
• 沸点: 114.7ºC at 760 mmHg
• 分子式: C₄H₈ClF
• 分子量: 110.55800
• 闪点: 9.9ºC
• 精确质量: 110.03000
• LogP: 1.97490
• 蒸汽压: 23.3mmHg at 25°C
• 折射率: 1.376
• 储存条件: 室温

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : EJ6530000 CHEMICAL NAME : Butane, 1-chloro-4-fluoro- CAS REGISTRY NUMBER : 462-73-7 BEILSTEIN REFERENCE NO. : 1697079 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C4-H8-Cl-F MOLECULAR WEIGHT : 110.57 WISWESSER LINE NOTATION : G4F HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1250 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JOCEAH Journal of Organic Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1936- Volume(issue)/page/year: 21,748,1956 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1250 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ont., Canada)

合成路线

928-51-8 ~63% 462-73-7

文献：Watanabe, S.; Fujita, T.; Usui, Y.; Kimura, Y. Journal of Fluorine Chemistry, 1986 , vol. 31, p. 135 - 142

26910-61-2 ~% 462-73-7

文献：Pattison; Millington Canadian Journal of Chemistry, 1956 , vol. 34, p. 757,760

110-56-5 ~% 462-73-7 372-90-7

文献：Hoffmann Journal of Organic Chemistry, 1950 , vol. 15, p. 425,427

6940-78-9 ~% 462-73-7 691-41-8

文献：Kartashov, A. V.; Chuvatkin, N. N.; Kurskii, Yu. A.; Boguslavskaya, L. S. Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 12 p. 2279 - 2284 Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 12 p. 2525 - 2531

110-56-5 ~% 462-73-7 691-41-8

文献：Kartashov, A. V.; Chuvatkin, N. N.; Kurskii, Yu. A.; Boguslavskaya, L. S. Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 12 p. 2279 - 2284 Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 12 p. 2525 - 2531

13617-19-1 ~% 462-73-7

文献：Robert,D.U. et al. Tetrahedron, 1973 , vol. 29, p. 1877 - 1885

2366-52-1 ~% 462-73-7 3824-16-6 691-40-7 详细

文献：Potter, Alan; Tedder, John M. Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1982 , p. 1689 - 1692

107-21-1 110-56-5 ~% 462-73-7 372-90-7

文献：Hoffmann Journal of Organic Chemistry, 1949 , vol. 14, p. 107

上下游产品

上游产品  7
928-51-8 26910-61-2 110-56-5 6940-78-9
13617-19-1 2366-52-1 107-21-1
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353-13-9 372-91-8