143426-49-7

• 常用中文名：4-(1-吡唑基)苄醇
• 常用英文名：(4-Pyrazol-1-ylphenyl)methanol
• CAS号：143426-49-7
• 分子式：C₁₀H₁₀N₂O
• 分子量：174.199
• 发布时间：2018-04-24 08:00:00
• 更新时间：2024-01-12 06:14:00

名称

• 中文名: 1-(4-羟甲基苯基)吡唑
• 英文名: (4-Pyrazol-1-yl-phenyl)methanol
• 中文别名: 4-吡唑-1-基苯甲醇; [4-(1H-吡唑-1-基)苯基]]乙醇; 4-(1-吡唑基)苄醇
• 英文别名: MFCD02682057; [4-(1-Pyrazolyl)phenyl]methanol; [4-(1H-Pyrazol-1-yl)phenyl]methanol; Benzenemethanol, 4-(1H-pyrazol-1-yl)-; (4-Pyrazol-1-ylphenyl)methanol

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 324.3±25.0 °C at 760 mmHg
• 熔点: 76-80ºC
• 分子式: C₁₀H₁₀N₂O
• 分子量: 174.199
• 闪点: 149.9±23.2 °C
• 精确质量: 174.079315
• PSA: 38.05000
• LogP: 0.93
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.605
• 储存条件: 2-8°C

MSDS

Name: [4-(1h-pyrazol-1-yl)phenyl]methanol 97% Material Safety Data Sheet Synonym: CAS: 143426-49-7 Section 1 - Chemical Product MSDS Name:[4-(1h-pyrazol-1-yl)phenyl]methanol 97% Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 143426-49-7 [4-(1H-Pyrazol-1-yl)phenyl]methanol 97% unlisted Hazard Symbols: XI Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 143426-49-7: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: off-white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 85 - 86 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C10H10N2O Molecular Weight: 174.2 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Oxidizing agents, reducing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 143426-49-7 unlisted. LD50/LC50: Not available. Carcinogenicity: [4-(1H-Pyrazol-1-yl)phenyl]methanol - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 143426-49-7: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 143426-49-7 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 143426-49-7 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xi:Irritant;
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): S26-S37/39

合成路线

143426-47-5 ~89% 143426-49-7

文献：Artico; Silvestri; Stefancich; Avigliano; Di Giulio; Maccarrone; Agostinelli; Mondovi; Morpurgo European Journal of Medicinal Chemistry, 1992 , vol. 27, # 3 p. 219 - 228

451-46-7 ~% 143426-49-7

文献：European Journal of Medicinal Chemistry, , vol. 27, # 3 p. 219 - 228

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