1558079-49-4

• 常用中文名：IR-825
• 常用英文名：IR-825
• CAS号：1558079-49-4
• 分子式：C₅₄H₄₈BrClN₂O₄
• 分子量：904.32700
• 发布时间：2018-12-10 16:14:34
• 更新时间：2024-04-06 10:25:49
• IR-825 is a near-infrared dye (NIR). IR-825, after encapsulated into nanoparticles may be useful for cancer photothermal and photodynamic therapy. IR-825 nanoparticles showed pH-dependent fluorescence emission and excellent near-infrared (NIR) irradiation of cancer cells targeted in vitro to provide cytotoxicity. IR-825 nanoparticles showed efficient tumor homing together with rapid renal excretion behaviors, as revealed by MR imaging and confirmed by biodistribution measurement. Notably, when irradiated with an 808 nm laser, tumors on mice with IR-825 nanoparticle injection are completely eliminated without recurrence within 60 days, demonstrating the high efficacy of photothermal therapy.

名称

• 英文名: ir825
• 英文别名: 3-(4-carboxybenzyl)-2-((E)-2-((E)-3-((E)-2-(3-(4-carboxybenzyl)-1,1-dimethyl-1,3-dihydro-2H-benzo[e]indol-2-ylidene)ethylidene)-2-chlorocyclohex-1-en-1-yl)vinyl)-1,1-dimethyl-1H-benzo[e]indol-3-ium bromide

物化性质

• 分子式: C₅₄H₄₈BrClN₂O₄
• 分子量: 904.32700
• 精确质量: 902.24900
• PSA: 80.85000
• LogP: 13.98900
• 储存条件: 2-8 °C

安全

• 危害码 (欧洲): Xn