483324-01-2

• 常用中文名：4-(3-吡啶基)-2-氯嘧啶
• 常用英文名：2-chloro-4-(pyridin-3-yl)pyriMidine
• CAS号：483324-01-2
• 分子式：C₉H₆ClN₃
• 分子量：191.617
• 相关类别： 医药中间体 杂环化合物 嘧啶类化合物 氯嘧啶
• 发布时间：2018-06-02 08:00:00
• 更新时间：2024-01-03 18:30:02

名称

• 中文名: 4-(3-吡啶基)-2-氯嘧啶
• 英文名: 2-chloro-4-pyridin-3-ylpyrimidine
• 英文别名: Pyrimidine, 2-chloro-4-(3-pyridinyl)-; 2-Chloro-4-(pyridin-3-yl)pyrimidine; 2-chloro-4-pyridin-3-yl-pyrimidine; 2-Chloro-4-(3-pyridinyl)pyrimidine

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 399.5±17.0 °C at 760 mmHg
• 分子式: C₉H₆ClN₃
• 分子量: 191.617
• 闪点: 227.7±6.5 °C
• 精确质量: 191.025024
• PSA: 38.67000
• LogP: 0.95
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.599
• 储存条件: 2-8°C，保存于惰性气体中

安全

• 海关编码: 2933990090

合成路线

3934-20-1 1692-25-7 ~73% 483324-01-2

文献：ZHANG, Dawei Patent: WO2011/8788 A1, 2011 ; Location in patent: Page/Page column 28-29 ; WO 2011/008788 A1

897031-20-8 ~57% 483324-01-2

文献：Anli, Huang; Xing, Liu; Zelikovitch, Lior; Kaspi, Joseph Patent: US2006/149061 A1, 2006 ; Location in patent: Page/Page column 8 ;

626-55-1 1722-12-9 ~94% 483324-01-2

文献：Bursavich, Matthew G.; Lombardi, Sabrina; Gilbert, Adam M. Organic Letters, 2005 , vol. 7, # 19 p. 4113 - 4116

1722-12-9 ~% 483324-01-2

文献：AMGEN INC. Patent: WO2008/11110 A2, 2008 ; Location in patent: Page/Page column 34-35 ;

626-55-1 3934-20-1 ~86% 483324-01-2

文献：Simkovsky, Nadja M.; Ermann, Monika; Roberts, Stanley M.; Parry, David M.; Baxter, Andy D. Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 16 p. 1847 - 1849

60573-68-4 1722-12-9 ~% 483324-01-2

文献：Gilbert, Adam M.; Bursavich, Matthew G.; Alon, Nippa; Bhat, Bheem M.; Bex, Frederick J.; Cain, Michael; Coleburn, Valerie; Gironda, Virginia; Green, Paula; Hauze, Diane B.; Kharode, Yogendra; Krishnamurthy, Girija; Kirisits, Matthew; Lam, Ho-Sun; Liu, Yao-Bin; Lombardi, Sabrina; Matteo, Jeanne; Murrills, Richard; Robinson, John A.; Selim, Sally; Sharp, Michael; Unwalla, Raymond; Varadarajan, Usha; Zhao, Weiguang; Yaworsky, Paul J. Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 1 p. 366 - 370

220565-63-9 3934-20-1 ~% 483324-01-2

文献：Anli, Huang; Xing, Liu; Zelikovitch, Lior; Kaspi, Joseph Patent: US2006/149061 A1, 2006 ; Location in patent: Page/Page column 7 ;

上下游产品

上游产品  7
3934-20-1 1692-25-7 897031-20-8 626-55-1
1722-12-9 60573-68-4 220565-63-9
下游产品  0

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%