124276-67-1

• 常用中文名：1-(4-溴苯基)环丙烷甲腈
• 常用英文名：1-(4-Bromophenyl)cyclopropanecarbonitrile
• CAS号：124276-67-1
• 分子式：C₁₀H₈BrN
• 分子量：222.081
• 发布时间：2018-07-05 19:02:31
• 更新时间：2024-01-11 21:35:19

名称

• 中文名: 1-(4-溴苯基)环丙烷甲腈
• 英文名: 1-(4-Bromophenyl)Cyclopropanecarbonitrile
• 中文别名: 环丙烷甲腈,1-(4-溴苯基)-; 3-(4'-溴苯基)环丙基甲氰
• 英文别名: 1-(4-Bromophenyl)cyclopropanecarbonitrile; 1-(4-Bromophenyl)-1-cyclopropanecarbonitrile; L3TJ ACN AR DE; Cyclopropanecarbonitrile, 1-(4-bromophenyl)-; 1-(4-bromophenyl)cyclopropane-1-carbonitrile; 1-(4-Bromophenyl)-1-cyanocyclopropane; Cyclopropanecarbonitrile,1-(4-bromophenyl)-

物化性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 321.4±35.0 °C at 760 mmHg
• 熔点: 84ºC
• 分子式: C₁₀H₈BrN
• 分子量: 222.081
• 闪点: 148.2±25.9 °C
• 精确质量: 220.984009
• PSA: 23.79000
• LogP: 2.31
• 外观性状: 白色固体
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.623
• 储存条件: 2-8℃

MSDS

Name: 1-(4-Bromophenyl)cyclopropanecarbonitrile Material Safety Data Sheet Synonym: CAS: 124276-67-1 Section 1 - Chemical Product MSDS Name:1-(4-Bromophenyl)cyclopropanecarbonitrile Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 124276-67-1 1-(4-Bromophenyl)cyclopropanecarbonitr unlisted Hazard Symbols: XN Risk Phrases: 20/21/22 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. Harmful if absorbed through the skin. Ingestion: Harmful if swallowed. May cause irritation of the digestive tract. Inhalation: Harmful if inhaled. Causes respiratory tract irritation. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 124276-67-1: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: Not available. Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 84 - 86 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C10H8BrN Molecular Weight: 222.08 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen bromide, bromine. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 124276-67-1 unlisted. LD50/LC50: Not available. Carcinogenicity: 1-(4-Bromophenyl)cyclopropanecarbonitrile - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: NITRILES, SOLID, TOXIC, N.O.S.* Hazard Class: 6.1 UN Number: 3276 Packing Group: II IMO Shipping Name: NITRILES, TOXIC, N.O.S. Hazard Class: 6.1 UN Number: 3276 Packing Group: II RID/ADR Shipping Name: NITRILES, TOXIC, N.O.S. Hazard Class: 6.1 UN Number: 3276 Packing group: II Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 124276-67-1: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 124276-67-1 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 124276-67-1 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xn:Harmful;
• 风险声明 (欧洲): R20/21/22;R36/37/38
• 安全声明 (欧洲): S26-S36/37/39
• 海关编码: 2926909090

合成路线

16532-79-9 107-04-0 ~99% 124276-67-1

文献：WO2013/189865 A1, ; Page/Page column 27 ;

16532-79-9 106-93-4 ~86% 124276-67-1

文献：US6359135 B1, ; Page column 113 ;

96-49-1 16532-79-9 ~51% 124276-67-1

文献：Tetrahedron Letters, , vol. 46, # 42 p. 7247 - 7248

上下游产品

上游产品  4
16532-79-9 107-04-0 106-93-4 96-49-1
下游产品  4
345965-52-8 1257213-52-7 1215205-50-7 847361-67-5

海关

海关编码	2926909090
中文概述	2926909090 其他腈基化合物. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%