450-91-9

• 常用中文名：4-氟-2-甲氧基苯胺
• 常用英文名：4-Fluoro-2-methoxyaniline
• CAS号：450-91-9
• 分子式：C₇H₈FNO
• 分子量：141.143
• 发布时间：2018-05-11 08:00:00
• 更新时间：2024-01-02 07:01:24

名称

• 中文名: 4-氟-2-邻甲氧基苯胺
• 英文名: 4-Fluoro-2-methoxyaniline
• 中文别名: 2-氨基-5-氟苯甲醚; 2-甲氧基-4-氟苯胺; 2-氨基-5-氟苯甲醚; 4-氟-2-甲氧基苯胺
• 英文别名: 4-Fluoro-2-methoxyaniline; Benzenamine, 4-fluoro-2-methoxy-

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 207.9±20.0 °C at 760 mmHg
• 分子式: C₇H₈FNO
• 分子量: 141.143
• 闪点: 79.5±21.8 °C
• 精确质量: 141.058990
• PSA: 35.25000
• LogP: 1.36
• 蒸汽压: 0.2±0.4 mmHg at 25°C
• 折射率: 1.532
• 储存条件: 室温

MSDS

Material Safety Data Sheet Section1. Identification of the substance Product Name: 4-Fluoro-2-methoxyaniline Synonyms: Section2. Hazards identification Harmful by inhalation, in contact with skin, and if swallowed. H331:Toxic if inhaled H302:Harmful if swallowed H312:Harmful in contact with skin Causes skin irritation H315: H319:Causes serious eye irritation H335:May cause respiratory irritation P261:Avoid breathing dust/fume/gas/mist/vapours/spray P280:Wear protective gloves/protective clothing/eye protection/face protection P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing P304+P340:IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing P405:Store locked up Section3. Composition/information on ingredients. Ingredient name:4-Fluoro-2-methoxyaniline CAS number:450-91-9 Section4. First aid measures Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing contaminated clothing and shoes. If irritation persists, seek medical attention. Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate Eye contact: flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical attention. Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention. Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention. Section5. Fire fighting measures In the event of a fire involving this material, alone or in combination with other materials, use dry powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus should be worn. Section6. Accidental release measures Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national standards. Respiratory precaution:Wear approved mask/respirator Hand precaution:Wear suitable gloves/gauntlets Skin protection:Wear suitable protective clothing Eye protection:Wear suitable eye protection Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container for disposal. See section 12. Environmental precautions: Do not allow material to enter drains or water courses. Section7. Handling and storage Handling:This product should be handled only by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals, who should take into account the fire, health and chemical hazard data given on this sheet. Storage:Store in closed vessels, refrigerated. Section8. Exposure Controls / Personal protection Engineering Controls: Use only in a chemical fume hood. Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles. General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse. Section9. Physical and chemical properties Not specified Appearance: Boiling point:No data Melting point:No data Flash point:No data Density:No data Molecular formula: C7H8FNO Molecular weight: 141.1 Section10. Stability and reactivity Conditions to avoid: Heat, flames and sparks. Materials to avoid: Oxidizing agents. Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen fluoride. Section11. Toxicological information No data. Section12. Ecological information No data. Section13. Disposal consideration Arrange disposal as special waste, by licensed disposal company, in consultation with local waste disposal authority, in accordance with national and regional regulations. Section14. Transportation information UN Number:UN2811Class: 6.1Packing group: III Proper shipping name: TOXIC SOLIDS, ORGANIC, N.O.S. (4-Fluoro-2-methoxyaniline) Section15. Regulatory information No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302, or have known CAS numbers that exceed the threshold reporting levels established by SARA Title III, Section 313. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xi
• 海关编码: 2922299090

合成路线

448-19-1 ~99% 450-91-9

文献：Yuhan Corporation Patent: US6352993 B1, 2002 ; Location in patent: Page column 30 ;

448-19-1 7440-02-0 ~% 450-91-9

文献：Mitsubishi Pharma Corporation Patent: US6455528 B1, 2002 ;

446-36-6 ~% 450-91-9

文献：Jacquet, Jean-Pierre; Bouzard, Daniel; Cesare, Pierre Di; Dolnic, Nicolas; Massoudi, Massoud; Remuzon, Philippe Heterocycles, 1992 , vol. 34, # 12 p. 2301 - 2311

456-49-5 ~% 450-91-9

文献：Nakata, Hisao; Jitsukawa, Fumie; Toyama, Hitomi; Kato, Yuko Organic Mass Spectrometry, 1992 , vol. 27, # 6 p. 720 - 723

上下游产品

上游产品  4
448-19-1 7440-02-0 446-36-6 456-49-5
下游产品  3
1075705-01-9 450-88-4 450-89-5

海关

海关编码	2922299090
中文概述	2922299090. 其他氨基(萘酚、酚)及醚、酯〔包括它们的盐, 但含有一种以上含氧基的除外〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
Summary	2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%