54940-95-3

• 常用中文名：邻丙氨酸硝苄芥
• 常用英文名：Nitrocaphane
• CAS号：54940-95-3
• 分子式：C₁₄H₁₉Cl₂N₃O₄
• 分子量：364.22400
• 相关类别： 生物化工 氨基酸及其衍生物 丙氨酸类衍生物
• 发布时间：2018-09-27 13:04:40
• 更新时间：2024-01-11 12:45:37

名称

• 中文名: 邻丙氨酸硝苄芥
• 英文名: Nitrocaphane/3
• 中文别名: 消瘤芥; 2[双(Β-氯乙基)胺甲基]-5-硝基茶丙氨酸
• 英文别名: Nitrocaphane; At-1258; Phenylalanine,2-((bis(2-chloroethyl)amino)methyl)-5-nitro; 2-((Bis(2-chloroethyl)amino)methyl)-5-nitrophenylalanine; 3-[2-[[Bis(2-chloroethyl)amino]methyl]-5-nitrophenyl]-2-aminopropionic acid; (S)-2-Amino-3-(2-((bis(2-chloroethyl)amino)methyl)-5-nitrophenyl)propanoic acid

物化性质

• 密度: 1.392g/cm3
• 沸点: 475.2ºC at 760 mmHg
• 分子式: C₁₄H₁₉Cl₂N₃O₄
• 分子量: 364.22400
• 闪点: 241.2ºC
• 精确质量: 363.07500
• PSA: 112.38000
• LogP: 3.05230
• 折射率: 1.595

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : SQ7329600 CHEMICAL NAME : Phenylalanine, 2-((bis(2-chloroethyl)amino)methyl)-5-nitro- CAS REGISTRY NUMBER : 54940-95-3 LAST UPDATED : 198305 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C14-H19-Cl2-N3-O4 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 50 mg/kg TOXIC EFFECTS : Tumorigenic - active as anti-cancer agent REFERENCE : CYLPDN Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1980- Volume(issue)/page/year: 2,121,1981 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 15100 ug/kg TOXIC EFFECTS : Tumorigenic - active as anti-cancer agent REFERENCE : CYLPDN Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1980- Volume(issue)/page/year: 2,121,1981