61220-36-8

• 常用中文名：四氢-1-(4-哌啶基)-2(1h)-嘧啶酮
• 常用英文名：1-(4-Piperidinyl)tetrahydro-2(1H)-pyrimidinone
• CAS号：61220-36-8
• 分子式：C₉H₁₇N₃O
• 分子量：183.251
• 发布时间：2018-12-20 13:21:15
• 更新时间：2024-01-16 15:55:51

名称

• 中文名: 四氢-1-(4-哌啶基)-2(1h)-嘧啶酮
• 英文名: 1-piperidin-4-yl-1,3-diazinan-2-one
• 英文别名: piperidinyldiazinanone; 1-(4-Piperidinyl)tetrahydro-2(1H)-pyrimidinone; 1-(piperidin-4-yl)tetrahydropyrimidin-2-one; 1-(4-piperidyl)-2-oxo-hexahydro-pyrimidine; 1-piperidinyl-4-yltetrahydropyrimidin-2[lH]-one; 4-(2-oxoperhydropyrimidine-1-yl)piperidine; 4-(tetrahydro-2-oxo-1(2H)-pyrimidinyl)piperidine; 2(1H)-Pyrimidinone,tetrahydro-1-(4-piperidinyl); Tetrahydro-1-(4-piperidinyl)-2(1H)-pyrimidinone; 2(1H)-Pyrimidinone, tetrahydro-1-(4-piperidinyl)-; 1-(piperidin-4-yl)tetrahydropyrimidin-2(1H)-one

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 397.2±31.0 °C at 760 mmHg
• 分子式: C₉H₁₇N₃O
• 分子量: 183.251
• 闪点: 194.0±24.8 °C
• 精确质量: 183.137161
• PSA: 47.86000
• LogP: 0.17
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.513

合成路线

61220-38-0 ~96% 61220-36-8

文献：SCHERING CORPORATION Patent: EP1144402 B1, 2004 ; Location in patent: Page 28; 31 ; EP 1144402 B1

164519-21-5 ~97% 61220-36-8

文献：Fujimoto, Takuya; Imaeda, Yasuhiro; Konishi, Noriko; Hiroe, Katsuhiko; Kawamura, Masaki; Textor, Garret P.; Aertgeerts, Kathleen; Kubo, Keiji Journal of Medicinal Chemistry, 2010 , vol. 53, # 9 p. 3517 - 3531

110-89-4 ~% 557-01-7 61220-36-8

文献：Zeneca Limited Patent: US5889024 A1, 1999 ;

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