136871-75-5

• 常用中文名：(2S,3S)-2-Phenyl-3-piperidinamine
• 常用英文名：(2S,3S)-2-Phenyl-3-piperidinamine
• CAS号：136871-75-5
• 分子式：C₁₁H₁₆N₂
• 分子量：176.25800
• 发布时间：2016-06-13 19:45:21
• 更新时间：2024-01-08 12:26:47

名称

• 英文名: (2S,3S)-2-Phenyl-3-piperidinamine
• 英文别名: NEBIVOLOL-D4; Nibivolol; rac-nebivolol

物化性质

• 分子式: C₁₁H₁₆N₂
• 分子量: 176.25800
• 精确质量: 176.13100
• PSA: 38.05000
• LogP: 2.46750

合成路线

32634-68-7 ~% 136871-75-5

文献：GLAXO GROUP LIMITED Patent: WO2008/90114 A1, 2008 ; Location in patent: Page/Page column 18 ; WO 2008/090114 A1

134896-35-8 ~% 136871-75-5

文献：Armour; Chung; Congreve; Evans; Guntrip; Hubbard; Kay; Middlemiss; Mordaunt; Pegg; Vinader; Ward; Watson Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 9 p. 1015 - 1020

98-80-6 ~% 136871-75-5

文献：Armour; Chung; Congreve; Evans; Guntrip; Hubbard; Kay; Middlemiss; Mordaunt; Pegg; Vinader; Ward; Watson Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 9 p. 1015 - 1020

1415550-83-2 ~% 136871-75-5

文献：Sultane, Prakash R.; Bhat, Ramakrishna G. Journal of Organic Chemistry, 2012 , vol. 77, # 24 p. 11349 - 11354

136982-36-0 ~% 136871-75-5

文献：Rosen, Terry J.; Coffman, Karen J.; McLean, Stafford; Crawford, Rosemary T.; Bryce, Dianne K.; Gohda, Yoshiko; Tsuchiya, Megumi; Nagahisa, Atsushi; Nakane, Masami; Lowe III, John A. Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 3 p. 281 - 284