797750-44-8

• 常用中文名：4-(4-氰基苯磺酰基)-哌啶-1-羧酸叔丁酯
• 常用英文名：4-(4-CYANO-BENZENESULFONYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
• CAS号：797750-44-8
• 分子式：C₁₇H₂₂N₂O₄S
• 分子量：350.43300
• 发布时间：2018-12-29 13:44:07
• 更新时间：2024-01-03 09:44:38

名称

• 中文名: 4-(4-氰基苯磺酰基)-哌啶-1-羧酸叔丁酯
• 英文名: tert-butyl 4-(4-cyanophenyl)sulfonylpiperidine-1-carboxylate
• 英文别名: tert-butyl 4-[(4-cyanobenzene)sulfonyl]piperidine-1-caboxylate; 1-Piperidinecarboxylicacid,4-[(4-cyanophenyl)sulfonyl]-,1,1-dimethylethyl ester; 4-[(N-BOC-Piperidin-4-yl)sulfonyl]benzonitrile; N-BOC 4-(piperidin-4-ylsulfonyl)benzonitrile; 4-(4-cyanobenzenesulfonyl)piperidine-1-carboxylic acid tert-butyl ester

物化性质

• 分子式: C₁₇H₂₂N₂O₄S
• 分子量: 350.43300
• 精确质量: 350.13000
• PSA: 95.85000
• LogP: 3.75018

合成路线

557-21-1 226398-62-5 ~90% 797750-44-8

文献：GENENTECH, INC.; FORMA TM, LLC; BAIR, Kenneth W.; BAUMEISTER, Timm R.; BUCKMELTER, Alexandre J.; CLODFELTER, Karl H.; DRAGOVICH, Peter; GOSSELIN, Francis; GUNZNER-TOSTE, Janet; HAN, Bingsong; LIN, Jian; LIU, Xiongcai; REYNOLDS, Dominic J.; SMITH, Chase C.; WANG, Zhongguo; ZAK, Mark; ZHANG, Yamin; ZHAO, Guiling; ZHENG, Xiaozhang; YUEN, Po-Wai Patent: WO2013/127266 A1, 2013 ; Location in patent: Page/Page column 153; 166 ;

188527-03-9 ~% 797750-44-8

文献：Dragovich, Peter S.; Bair, Kenneth W.; Baumeister, Timm; Ho, Yen-Ching; Liederer, Bianca M.; Liu, Xiongcai; Liu, Yongbo; O'Brien, Thomas; Oeh, Jason; Sampath, Deepak; Skelton, Nicholas; Wang, Leslie; Wang, Weiru; Wu, Hongxing; Xiao, Yang; Yuen, Po-Wai; Zak, Mark; Zhang, Lei; Zheng, Xiaozhang Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 17 p. 4875 - 4885

109384-19-2 ~% 797750-44-8

文献：Dragovich, Peter S.; Bair, Kenneth W.; Baumeister, Timm; Ho, Yen-Ching; Liederer, Bianca M.; Liu, Xiongcai; Liu, Yongbo; O'Brien, Thomas; Oeh, Jason; Sampath, Deepak; Skelton, Nicholas; Wang, Leslie; Wang, Weiru; Wu, Hongxing; Xiao, Yang; Yuen, Po-Wai; Zak, Mark; Zhang, Lei; Zheng, Xiaozhang Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 17 p. 4875 - 4885

106-53-6 ~% 797750-44-8

文献：Dragovich, Peter S.; Bair, Kenneth W.; Baumeister, Timm; Ho, Yen-Ching; Liederer, Bianca M.; Liu, Xiongcai; Liu, Yongbo; O'Brien, Thomas; Oeh, Jason; Sampath, Deepak; Skelton, Nicholas; Wang, Leslie; Wang, Weiru; Wu, Hongxing; Xiao, Yang; Yuen, Po-Wai; Zak, Mark; Zhang, Lei; Zheng, Xiaozhang Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 17 p. 4875 - 4885

5382-16-1 ~% 797750-44-8

文献：GENENTECH, INC.; FORMA TM, LLC; BAIR, Kenneth W.; BAUMEISTER, Timm R.; BUCKMELTER, Alexandre J.; CLODFELTER, Karl H.; DRAGOVICH, Peter; GOSSELIN, Francis; GUNZNER-TOSTE, Janet; HAN, Bingsong; LIN, Jian; LIU, Xiongcai; REYNOLDS, Dominic J.; SMITH, Chase C.; WANG, Zhongguo; ZAK, Mark; ZHANG, Yamin; ZHAO, Guiling; ZHENG, Xiaozhang; YUEN, Po-Wai Patent: WO2013/127266 A1, 2013 ;

24424-99-5 ~% 797750-44-8

文献：GENENTECH, INC.; FORMA TM, LLC; BAIR, Kenneth W.; BAUMEISTER, Timm R.; BUCKMELTER, Alexandre J.; CLODFELTER, Karl H.; DRAGOVICH, Peter; GOSSELIN, Francis; GUNZNER-TOSTE, Janet; HAN, Bingsong; LIN, Jian; LIU, Xiongcai; REYNOLDS, Dominic J.; SMITH, Chase C.; WANG, Zhongguo; ZAK, Mark; ZHANG, Yamin; ZHAO, Guiling; ZHENG, Xiaozhang; YUEN, Po-Wai Patent: WO2013/127266 A1, 2013 ;

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