245110-80-9

245110-80-9结构式

常用中文名：Paclitaxel succinate NHS ester
常用英文名：Paclitaxel succinate NHS ester
CAS号：245110-80-9
分子式：C₅₅H₅₈N₂O₁₉
分子量：1051.051
发布时间：2021-01-07 19:03:13
更新时间：2024-01-13 15:41:10
DCN10809, also known as Paclitaxel succinate NHS ester, is a paclitaxel derivative with a succinic acid linker, in which the carboxy group is activated with an NHS ester. The NHS ester group is highly reactive to amino group or hydroxy group, and can be used to conjugate with other molecules such as peptides, proteins, antibodies or enzymes, or polymers. Paclitaxel-Succinic acid is a useful agent to make Paclitaxel-conjugate for drug delivery, nanodrug research.

英文名	(2α,5β,7β,10β,13α)-4,10-Diacetoxy-13-{[(2R,3S)-3-(benzoylamino)-2-({4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxobutanoyl}oxy)-3-phenylpropanoyl]oxy}-1,7-dihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
英文别名	(2α,5β,7β,10β,13α)-4,10-Diacetoxy-13-{[(2R,3S)-3-(benzoylamino)-2-({4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxobutanoyl}oxy)-3-phenylpropanoyl]oxy}-1,7-dihydroxy-9-oxo-5,20-epoxytax-11-en -2-yl benzoate Benzenepropanoic acid, β-(benzoylamino)-α-[4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,4-dioxobutoxy]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,1 2,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-