735-52-4

• 常用中文名：乙酰氯霉素
• 常用英文名：Acetamide,N-[(1R,2R)-2-(4-acetylphenyl)-2-hydroxy-1-(hydroxymethyl)ethyl]-2,2-dichloro-
• CAS号：735-52-4
• 分子式：C₁₃H₁₅Cl₂NO₄
• 分子量：320.16900
• 发布时间：2018-04-17 08:00:00
• 更新时间：2024-01-08 19:04:38

名称

• 中文名: 乙酰氯霉素
• 英文名: N-[1-(4-acetylphenyl)-1,3-dihydroxypropan-2-yl]-2,2-dichloroacetamide
• 英文别名: Cetofenicol; CETOPHENICOL; Acetylchloramphenicol; D-Threoacetomycetin; Acetamide,2-dichloro-,D-threo; W 3746

物化性质

• 分子式: C₁₃H₁₅Cl₂NO₄
• 分子量: 320.16900
• 精确质量: 319.03800
• PSA: 86.63000
• LogP: 1.59430

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : AB4200000 CHEMICAL NAME : Acetamide, N-(p-acetyl-beta-hydroxy-alpha-(hydroxymethyl)pheneth yl)-2,2-dichloro-, D-threo- CAS REGISTRY NUMBER : 735-52-4 LAST UPDATED : 199106 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C13-H15-Cl2-N-O4 MOLECULAR WEIGHT : 320.19 WISWESSER LINE NOTATION : GYGVMY1QYQR DV1 -D -THREO HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1097 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 18,185,1971 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 5200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 10,888,1967