51454-63-8

• 常用中文名：4-氰基吡啶-2-甲醇
• 常用英文名：4-cyano-pyridine-2-methanol
• CAS号：51454-63-8
• 分子式：C₇H₆N₂O
• 分子量：134.135
• 相关类别： 医药中间体 杂环化合物 吡啶类化合物 氰基吡啶
• 发布时间：2018-06-30 16:56:22
• 更新时间：2024-01-09 17:24:21

名称

• 中文名: 2-羟基甲基-4-吡啶甲腈
• 英文名: 2-(hydroxymethyl)pyridine-4-carbonitrile
• 中文别名: 4-氰基吡啶-2-甲醇; 2 - (羟甲基)吡啶- 4 -腈; 2-(羟甲基)吡啶-4-腈
• 英文别名: 4-Cyanopyrid-2-ylcarbinol; 2-Hydroxymethyl-4-cyanopyridine; 2-(hydroxymethyl)-4-pyridinecarbonitrile; 4-Pyridinecarbonitrile, 2-(hydroxymethyl)-; 4-cyano-2-hydroxymethylpyridine; 4-cyano-pyridine-2-methanol; 2-(Hydroxymethyl)isonicotinonitrile

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 282.4±25.0 °C at 760 mmHg
• 分子式: C₇H₆N₂O
• 分子量: 134.135
• 闪点: 124.6±23.2 °C
• 精确质量: 134.048019
• PSA: 56.91000
• LogP: -0.78
• 蒸汽压: 0.0±0.6 mmHg at 25°C
• 折射率: 1.575
• 储存条件: 室温，干燥密封

安全

• 海关编码: 2933399090

合成路线

100-48-1 67-56-1 ~38% 51454-63-8

文献：SHIONOGI and CO., LTD.; EURO-CELTIQUE S.A Patent: WO2008/8398 A2, 2008 ; Location in patent: Page/Page column 356 ;

51454-62-7 ~70% 51454-63-8

文献：Ashimori; Ono; Uchida; Ohtaki; Fukaya; Watanabe; Yokoyama Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 9 p. 2446 - 2458

2950-43-8 ~25% 51454-63-8

文献：KUDOS PHARMACEUTICALS LIMITED Patent: WO2006/21801 A1, 2006 ; Location in patent: Page/Page column 65-66 ; WO 2006/021801 A1

14906-59-3 ~% 51454-63-8

文献：Katz, R B; Mistry, J; Mitchell, M B Synthetic Communications, 1989 , vol. 19, # 1, 2 p. 317 - 326

931-19-1 ~% 51454-63-8

文献：Ashimori; Ono; Uchida; Ohtaki; Fukaya; Watanabe; Yokoyama Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 9 p. 2446 - 2458

2214-53-1 ~% 51454-63-8

文献：Ashimori; Ono; Uchida; Ohtaki; Fukaya; Watanabe; Yokoyama Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 9 p. 2446 - 2458

98549-84-9 ~% 51454-63-8

文献：Ashimori; Ono; Uchida; Ohtaki; Fukaya; Watanabe; Yokoyama Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 9 p. 2446 - 2458

30342-68-8 ~% 51454-63-8

文献：Ashimori; Ono; Uchida; Ohtaki; Fukaya; Watanabe; Yokoyama Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 9 p. 2446 - 2458

上下游产品

上游产品  8
100-48-1 67-56-1 51454-62-7 2950-43-8
14906-59-3 931-19-1 2214-53-1 98549-84-9
下游产品  1
116308-38-4

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%