1422966-97-9

1422966-97-9结构式

常用中文名：(±)-顺式-N-Boc-4-氟环己胺
常用英文名：(±)-cis-N-Boc-4-fluorocyclohexylamine
CAS号：1422966-97-9
分子式：C₁₁H₂₀FNO₂
分子量：217.28
发布时间：2023-01-17 16:48:52
更新时间：2024-04-11 07:51:09
Description The incorporation of fluorine in agrochemical and pharmaceutical compounds is of high interest due to the ability to fine-tune the polarity, pKA-value, conformation and metabolic stability. Derived from acis-selective hydrogenation developed by Glorius and coworkers, this fluorinated compound displays a diverse utility as a building block for chemical synthesis. Fluoro-cyclohexaneamine allows for the straightforward application in organic synthesis, after simple deprotection. It has been shown, that this compound can be used for the preparation of fluorinated analogs of Lomustine and Bromhexine. Description The incorporation of fluorine in agrochemical and pharmaceutical compounds is of high interest due to the ability to fine-tune the polarity, pKA-value, conformation and metabolic stability. Derived from acis-selective hydrogenation developed by Glorius and coworkers, this fluorinated compound displays a diverse utility as a building block for chemical synthesis. Fluoro-cyclohexaneamine allows for the straightforward application in organic synthesis, after simple deprotection. It has been shown, that this compound can be used for the preparation of fluorinated analogs of Lomustine and Bromhexine.

中文名	(±)-顺式-N-Boc-4-氟环己胺
英文名	(±)-cis-N-Boc-4-fluorocyclohexylamine
英文别名	2-Methyl-2-propanyl (cis-4-fluorocyclohexyl)carbamate Carbamic acid, N-(cis-4-fluorocyclohexyl)-, 1,1-dimethylethyl ester MFCD18434519