707-09-5

• 常用中文名：3-methyl-1,3-diazaspiro[4.5]decane-2,4-dione
• 常用英文名：3-methyl-1,3-diazaspiro[4.5]decane-2,4-dione
• CAS号：707-09-5
• 分子式：C₉H₁₄N₂O₂
• 分子量：182.22000
• 发布时间：2016-12-24 23:56:41
• 更新时间：2024-01-23 21:19:20

名称

• 英文名: 3-methyl-1,3-diazaspiro[4.5]decane-2,4-dione
• 英文别名: 3'-Methyl-cyclohexanspiro-5'-hydantoin; 3'-Methylcyclohexanespiro-5'-hydantoin; 3-Methyl-5,5-pentamethylen-hydantoin; 1,4-dione,3-methyl

物化性质

• 密度: 1.22g/cm3
• 分子式: C₉H₁₄N₂O₂
• 分子量: 182.22000
• 精确质量: 182.10600
• PSA: 49.41000
• LogP: 1.13760
• 折射率: 1.548

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : HM2770000 CHEMICAL NAME : 1,3-Diazaspiro(4.5)decane-2,4-dione, 3-methyl- CAS REGISTRY NUMBER : 707-09-5 BEILSTEIN REFERENCE NO. : 0157527 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C9-H14-N2-O2 MOLECULAR WEIGHT : 182.25 WISWESSER LINE NOTATION : T5MVNVXJ C1 E-& AL6XTJ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1100 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - stiffness REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,239,1965

合成路线

702-62-5 77-78-1 ~74% 707-09-5

文献：Pedregal; Trigo; Espada; et al. Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 2 p. 477 - 480

702-62-5 74-88-4 ~% 707-09-5

文献：Lilly Industries Limited Patent: US4230709 A1, 1980 ;

2756-85-6 ~% 707-09-5

文献：Courtoison; Coudert; Couquelet; Tronche; Jonadet; Bastide Farmaco, Edizione Scientifica, 1988 , vol. 43, # 2 p. 153 - 160

4507-57-7 624-83-9 ~34% 707-09-5

文献：Courtoison; Coudert; Couquelet; Tronche; Jonadet; Bastide Farmaco, Edizione Scientifica, 1988 , vol. 43, # 2 p. 153 - 160

702-62-5 ~% 707-09-5

文献：Salazar, Loreto; Rubido, Julia; Espada, Modesta; Pedregal, Carmen; Trigo, Gregorio; Elguero, Jose Journal of Heterocyclic Chemistry, 1986 , vol. 23, p. 481 - 485

186581-53-3 702-62-5 ~% 707-09-5

文献：Carrington; Waring Journal of the Chemical Society, 1950 , p. 354,366

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