6035-40-1

• 常用中文名：(-)-alpha-Narcotine
• 常用英文名：(-)-alpha-Narcotine
• CAS号：6035-40-1
• 分子式：C₂₂H₂₃NO₇
• 分子量：413.42100
• 发布时间：2016-03-04 11:52:16
• 更新时间：2024-02-12 08:25:21

名称

• 英文名: ( -)-α-Narcotine

物化性质

• 密度: 1.332g/cm3
• 沸点: 565.3ºC at 760 mmHg
• 熔点: 176ºC
• 分子式: C₂₂H₂₃NO₇
• 分子量: 413.42100
• 闪点: 295.7ºC
• 精确质量: 413.14700
• PSA: 75.69000
• LogP: 2.81970
• 折射率: 1.602

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : QN5600000 CHEMICAL NAME : Narcotine, (+-)- CAS REGISTRY NUMBER : 6035-40-1 LAST UPDATED : 199512 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C22-H23-N-O7 MOLECULAR WEIGHT : 413.46 WISWESSER LINE NOTATION : T C566 DO FO KN EH&&TJ HO1 K1 J- DT56 BVO DHJ HO1 IO1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 750 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 6,235,1950 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2784 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 15,640,1957 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 491 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 15,640,1957 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 83 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 8(1),206,1982 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 73 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 7,372,1959