352-21-6
352-21-6结构式
- 常用中文名：3-羟基-4-氨基丁酸
- 常用英文名：DL-γ-Amino-β-hydroxybutyric acid
- CAS号：352-21-6
- 分子式：C4H9NO3
- 分子量：119.119
- 相关类别： 化学试剂 有机试剂 脂肪酸
- 发布时间：2018-08-20 21:46:54
- 更新时间：2024-01-11 11:35:13
| 中文名 | Alpha-羟基-γ-氨基丁酸 |
|---|---|
| 英文名 | 4-amino-3-hydroxybutanoate |
| 中文别名 |
GABOB( 3-羟基-4-氨基丁酸)
3-羟基-4-氨基丁酸 |
| 英文别名 |
gabomade
3-Hydroxy-4-aminobutyric acid γ-amino-β-hydroxybutyric acid gamibetal Aminohydroxybutyricacid 3-hydroxy-4-amino-butyric acid (GABOB) 3-hydroxy-GABA β-Hydroxy-GABA 3-hydroxy-4-amino-butyric acid Butanoic acid, 4-amino-3-hydroxy- buksamin 4-amino-3-hydroxy-butyricaci β-Hydroxy-γ-aminobutyric acid EINECS 206-518-5 4-Amino-3-hydroxybutanoic acid g-Amino-b-hydroxybutyric Acid DL-4-Amino-3-hydroxybutanoic acid .γ.-Amino-.β.-hydroxybutyric acid DL-4-Amino-3-hydroxybutyric acid (±)-4-Amino-3-hydroxybutyric acid γ-Amino-β-hydroxy-n-butyric acid 4-Amino-3-hydroxybutanoate UNII:1ZHM019FLD |
| 密度 | 1.3±0.1 g/cm3 |
|---|---|
| 沸点 | 374.5±32.0 °C at 760 mmHg |
| 熔点 | 157-161ºC |
| 分子式 | C4H9NO3 |
| 分子量 | 119.119 |
| 闪点 | 180.3±25.1 °C |
| 精确质量 | 119.058243 |
| PSA | 83.55000 |
| LogP | -1.73 |
| 外观性状 | 白色粉末 |
| 蒸汽压 | 0.0±1.9 mmHg at 25°C |
| 折射率 | 1.511 |
| 储存条件 | 储运特性:库房通风低温干燥 |
| 分子结构 | 1、 摩尔折射率：27.17 2、 摩尔体积（m3/mol）：90.7 3、 等张比容（90.2K）：256.2 4、 表面张力（dyne/cm）：63.5 5、 极化率（10 -24cm 3）：10.77 |
| 计算化学 | 1.疏水参数计算参考值（XlogP）:-4.1 2.氢键供体数量:3 3.氢键受体数量:4 4.可旋转化学键数量:3 5.互变异构体数量:无 6.拓扑分子极性表面积83.6 7.重原子数量:8 8.表面电荷:0 9.复杂度:83.4 10.同位素原子数量:0 11.确定原子立构中心数量:0 12.不确定原子立构中心数量:1 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:1 |
| 更多 | 一、物性数据 性状：不可用 密度（g/mL,25/4℃）：不可用 相对蒸汽密度（g/mL,空气=1）：不可用 熔点（ºC）：157-161 沸点（ºC,常压）：不可用 沸点（ºC,5.2kPa）：不可用 折射率：不可用 闪点（ºC）：不可用 比旋光度（º）：不可用 自燃点或引燃温度（ºC）：不可用 蒸气压（kPa,25ºC）：不可用 饱和蒸气压（kPa,60ºC）：不可用 燃烧热（KJ/mol）：不可用 临界温度（ºC）：不可用 临界压力（KPa）：不可用 油水（辛醇/水）分配系数的对数值：不可用 爆炸上限（%,V/V）：不可用 爆炸下限（%,V/V）：不可用 溶解性：不可用 |
Synonym:Beta-Hydroxy-Alpha-Aminobutyric Acid Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: None Listed. Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Not available. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Ingestion: May cause irritation of the digestive tract. Low hazard for usual industrial handling. Inhalation: May cause respiratory tract irritation. Low hazard for usual industrial handling. Chronic: No information found. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation develops, get medical aid. Skin: Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse. Ingestion: Never give anything by mouth to an unconscious person. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water. Get medical aid if irritation or symptoms occur. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. No special precautions indicated. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 352-21-6: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Powder Color: white Odor: None reported. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 202 deg C Autoignition Temperature: Not applicable. Flash Point: Not applicable. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: soluble Specific Gravity/Density: Molecular Formula: H2NCH2CH(OH)CH2CO2H Molecular Weight: 119.12 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials, dust generation, excess heat, strong oxidants. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide. Hazardous Polymerization: Has not been reported. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 352-21-6 unlisted. LD50/LC50: Not available. Carcinogenicity: DL-4-Amino-3-Hydroxybutyric Acid - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. S 28A After contact with skin, wash immediately with plenty of water. S 37 Wear suitable gloves. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 352-21-6: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 352-21-6 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 352-21-6 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
|
毒理学数据: 二、毒理学数据： 急性毒性：不可用。 生态学数据: 三、生态学数据： 1、其它有害作用：该物质对环境可能有危害，对水体应给予特别注意。 CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|