159635-22-0

• 常用中文名：3-羟基-4-亚甲基哌啶-1-甲酸叔丁酯
• 常用英文名：tert-Butyl 3-hydroxy-4-methylenepiperidine-1-carboxylate
• CAS号：159635-22-0
• 分子式：C₁₁H₁₉NO₃
• 分子量：213.273
• 发布时间：2017-04-18 09:49:24
• 更新时间：2024-01-09 13:45:30

名称

• 中文名: 3-羟基-4-亚甲基哌啶-1-甲酸叔丁酯
• 英文名: tert-butyl 3-hydroxy-4-methylidenepiperidine-1-carboxylate
• 英文别名: 1-Piperidinecarboxylic acid, 3-hydroxy-4-methylene-, 1,1-dimethylethyl ester; 2-Methyl-2-propanyl 3-hydroxy-4-methylene-1-piperidinecarboxylate; 1-t-butoxycarbonyl-3-hydroxy-4-methylenepiperidine; W3461; 1-Boc-3-Hydroxy-4-methylenepiperidine; 3-hydroxy-4-methylene-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 3-hydroxy-4-methylene-piperidine-1-carboxylic acid tert-butyl ester; 1-[(1,1-dimethylethoxy)carbonyl]-3-hydroxy-4-methylene-1,2,5,6-tetrahydropyridine; tert-Butyl 3-hydroxy-4-methylenepiperidine-1-carboxylate; N-T-BOC-4-METHYLENE-3-PIPERIDINOL

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 309.0±42.0 °C at 760 mmHg
• 分子式: C₁₁H₁₉NO₃
• 分子量: 213.273
• 闪点: 140.7±27.9 °C
• 精确质量: 213.136490
• PSA: 49.77000
• LogP: 0.93
• 蒸汽压: 0.0±1.5 mmHg at 25°C
• 折射率: 1.503
• 储存条件: 2-8°C，干燥密封

安全

• 海关编码: 2933399090

合成路线

159635-49-1 ~63% 159635-22-0

文献：Vice; Bara; Bauer; Evans; Ford; Josien; McCombie; Miller; Nazareno; Palani; Tagat Journal of Organic Chemistry, 2001 , vol. 66, # 7 p. 2487 - 2492

221142-27-4 ~75% 159635-22-0

文献：JANSSEN PHARMACEUTICA, N.V. Patent: WO2009/67202 A1, 2009 ; Location in patent: Page/Page column 143 ; WO 2009/067202 A1

79099-07-3 ~% 159635-22-0

文献：WO2013/80222 A1, ;

上下游产品

上游产品  2
159635-49-1 79099-07-3
下游产品  0

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%