444583-19-1

• 常用中文名：(R)-3-甲酰基-3,4-二氢-1H-异喹啉-2-羧酸叔丁酯
• 常用英文名：(R)-3-FORMYL-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER
• CAS号：444583-19-1
• 分子式：C₁₅H₁₉NO₃
• 分子量：261.31600
• 发布时间：2018-12-31 09:16:20
• 更新时间：2024-01-21 09:50:04

名称

• 中文名: (R)-3-甲酰基-3,4-二氢-1H-异喹啉-2-羧酸叔丁酯
• 英文名: tert-butyl (3R)-3-formyl-3,4-dihydro-1H-isoquinoline-2-carboxylate

物化性质

• 分子式: C₁₅H₁₉NO₃
• 分子量: 261.31600
• 精确质量: 261.13600
• PSA: 46.61000
• LogP: 2.48520

合成路线

845543-81-9 ~90% 444583-19-1

文献：Bristol-Myers Squibb Company Patent: US2008/153868 A1, 2008 ; Location in patent: Page/Page column 16 ; US 20080153868 A1

444583-18-0 ~99% 444583-19-1

文献：Wacker, Dean A.; Zhao, Guohua; Kwon, Chet; Varnes, Jeffrey G.; Stein, Philip D. Patent: US2005/80074 A1, 2005 ; Location in patent: Page/Page column 72 ;

78879-20-6 ~% 444583-19-1

文献：Shi, Qing; Ornstein, Paul L.; Briner, Karin; Richardson, Timothy I.; Arnold, Macklin B.; Backer, Ryan T.; Buckmaster, Jennifer L.; Canada, Emily J.; Doecke, Christopher W.; Hertel, Larry W.; Honigschmidt, Nick; Hsiung, Hansen M.; Husain, Saba; Kuklish, Steve L.; Martinelli, Michael J.; Mullaney, Jeffrey T.; O'Brien, Thomas P.; Reinhard, Matt R.; Rothhaar, Roger; Shah, Jikesh; Wu, Zhipei; Xie, Chaoyu; Zgombick, John M.; Fisher, Matthew J. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 9 p. 2341 - 2346

183958-71-6 ~% 444583-19-1 145525-27-5

文献：Aubry, Sylvain; Pellet-Rostaing, Stephane; Fenet, Bernard; Lemaire, Marc Tetrahedron Letters, 2006 , vol. 47, # 8 p. 1319 - 1323

18881-17-9 ~% 444583-19-1

文献：Aubry, Sylvain; Pellet-Rostaing, Stephane; Fenet, Bernard; Lemaire, Marc Tetrahedron Letters, 2006 , vol. 47, # 8 p. 1319 - 1323

24424-99-5 ~% 444583-19-1

文献：Aubry, Sylvain; Pellet-Rostaing, Stephane; Fenet, Bernard; Lemaire, Marc Tetrahedron Letters, 2006 , vol. 47, # 8 p. 1319 - 1323

上下游产品

上游产品  5
845543-81-9 78879-20-6 183958-71-6 18881-17-9
24424-99-5
下游产品  0