5632-44-0

• 常用中文名：托普帕敏
• 常用英文名：tolpropamine
• CAS号：5632-44-0
• 分子式：C₁₈H₂₃N
• 分子量：253.38200
• 相关类别： 原料药 抗变态反应药 抗组胺药
• 发布时间：2018-09-16 12:55:30
• 更新时间：2024-01-06 22:08:23

名称

• 中文名: 托普帕敏
• 英文名: N,N-Dimethyl-3-(4-methylphenyl)-3-phenyl-1-propanamine
• 英文别名: 1-[3-(4-methylphenyl)-3-phenylpropyl]-N,N-dimethylamine; tolpropamine; N,N-dimethyl-3-phenyl-3-(p-tolyl)propylamine; 4-(3-imidazol-1-yl-1-methyl-propyl)-phenol; Tolpropamid; Phenol,4-[3-(1H-imidazol-1-yl)-1-methylpropyl]; N,N-dimethyl-3-phenyl-3-(p-tolyl)propan-1-amine; 1-Phenyl-1-p-tolyl-3-dimethylamino-propan; 4-[3-(1-imidazolyl)-1-methylpropyl]-phenol; 1-[3-(4-hydroxyphenyl)butyl]imidazole

物化性质

• 分子式: C₁₈H₂₃N
• 分子量: 253.38200
• 精确质量: 253.18300
• PSA: 3.24000
• LogP: 4.07860

合成路线

201230-82-2 948-55-0 124-40-3 ~84% 5632-44-0

文献：Ahmed, Moballigh; Buch, Cathleen; Routaboul, Lucie; Jackstell, Ralf; Klein, Holger; Spannenberg, Anke; Beller, Matthias Chemistry - A European Journal, 2007 , vol. 13, # 5 p. 1594 - 1601

92804-29-0 124-40-3 ~% 5632-44-0

文献：Botteghi; Cazzolato; Marchetti; Paganelli Journal of Organic Chemistry, 1995 , vol. 60, # 20 p. 6612 - 6615

58574-44-0 ~% 5632-44-0

文献：Selvamurugan; Aidhen Synthesis, 2001 , # 15 p. 2239 - 2246

4294-57-9 ~% 5632-44-0

文献：Selvamurugan; Aidhen Synthesis, 2001 , # 15 p. 2239 - 2246

3506-36-3 ~% 5632-44-0

文献：Selvamurugan; Aidhen Synthesis, 2001 , # 15 p. 2239 - 2246

405212-55-7 ~% 5632-44-0

文献：Selvamurugan; Aidhen Synthesis, 2001 , # 15 p. 2239 - 2246

23426-02-0 ~% 5632-44-0

文献：Prediger, Patricia; Da Silva, Allan Ribeiro; Correia, Carlos Roque Duarte Tetrahedron, 2014 , vol. 70, # 20 p. 3333 - 3341

4073-42-1 ~% 5632-44-0

文献：Prediger, Patricia; Da Silva, Allan Ribeiro; Correia, Carlos Roque Duarte Tetrahedron, 2014 , vol. 70, # 20 p. 3333 - 3341

7364-22-9 107-99-3 ~% 5632-44-0

文献：Azzena; Melloni; Fenude; Fina; Marchetti; Sechi Synthetic Communications, 1994 , vol. 24, # 5 p. 591 - 599

上下游产品

上游产品  9
201230-82-2 948-55-0 124-40-3 58574-44-0
4294-57-9 3506-36-3 405212-55-7 23426-02-0
4073-42-1
下游产品  0