69159-50-8

• 常用中文名：1-(二苯基环庚基)-哌嗪
• 常用英文名：1-(dibenzosuberyl)piperazine
• CAS号：69159-50-8
• 分子式：C₁₉H₂₂N₂
• 分子量：278.39100
• 相关类别： 医药中间体 杂环化合物 哌嗪类化合物
• 发布时间：2018-04-21 08:00:00
• 更新时间：2024-01-11 15:57:10

名称

• 中文名: 1-二苯环庚基哌嗪
• 英文名: 1-(6,11-dihydro-5H-dibenzo[1,2-a:1',2'-e][7]annulen-11-yl)piperazine
• 中文别名: 1-(二苯基环庚基)-哌嗪
• 英文别名: OR1479; 1-(10,11-dihydro-5H-dibenzo<a,d>cycloheptene-5-yl)piperazine; 1-(10,11-Dihydrodibenzo(a,d)cyclohepten-5-yl)piperazine; 5-(Suberan-5-yl)piperazine; 1-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-piperazine; 5-PIPERAZINYL 10,11-DIHYDRO-5H-DIBENZO[a,d]CYCLOHEPTENE; MFCD01703212; Piperazine,1-(10,11-dihydrodibenzo(a,d)cyclohepten-5-yl); 1-(Dibenzosuberyl)-piperazine; N-(10,11-dihydro-5H-dibenzo<a,d>cycloheptan-5-yl)piperazine

物化性质

• 密度: 1.109g/cm3
• 沸点: 402.9ºC at 760 mmHg
• 熔点: 105-107ºC
• 分子式: C₁₉H₂₂N₂
• 分子量: 278.39100
• 闪点: 154.7ºC
• 精确质量: 278.17800
• PSA: 15.27000
• LogP: 3.04650
• 折射率: 1.604

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TL4042500 CHEMICAL NAME : Piperazine, 1-(10,11-dihydrodibenzo(a,d)cyclohepten-5-yl)- CAS REGISTRY NUMBER : 69159-50-8 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C19-H22-N2 MOLECULAR WEIGHT : 278.43 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >50 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 22,183,1979

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933599090

合成路线

110-85-0 1210-33-9 ~85% 69159-50-8

文献：Suzuki, Tsuneji; Fukazawa, Nobuyuki; San-nohe, Kunio; Sato, Wakao; Yano, Osamu; Tsuruo, Takashi Journal of Medicinal Chemistry, 1997 , vol. 40, # 13 p. 2047 - 2052

108-20-3 1210-33-9 ~% 69159-50-8

文献：US5422351 A1, ;

121942-85-6 ~% 69159-50-8

文献：Collection of Czechoslovak Chemical Communications, , vol. 53, # 4 p. 870 - 883

1210-34-0 ~% 69159-50-8

文献：Collection of Czechoslovak Chemical Communications, , vol. 53, # 4 p. 870 - 883

1210-33-9 ~% 69159-50-8

文献：Collection of Czechoslovak Chemical Communications, , vol. 53, # 4 p. 870 - 883

上下游产品

上游产品  5
110-85-0 1210-33-9 108-20-3 121942-85-6
1210-34-0
下游产品  0

海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%