CHEMICAL IDENTIFICATION
-
RTECS NUMBER :
-
KE6345210
-
CHEMICAL NAME :
-
Ergoline-8-beta-propionitrile, 6-methyl-alpha-(4-methyl-1-piperazinylcarbonyl)-
-
CAS REGISTRY NUMBER :
-
74627-31-9
-
LAST UPDATED :
-
199309
-
DATA ITEMS CITED :
-
2
-
MOLECULAR FORMULA :
-
C24-H31-N5-O
-
MOLECULAR WEIGHT :
-
405.60
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
-
TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
400 mg/kg
-
TOXIC EFFECTS :
-
Vascular - BP lowering not characterized in autonomic section
-
REFERENCE :
-
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 33,1094,1983 ** REPRODUCTIVE DATA **
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Oral
-
DOSE :
-
16 mg/kg
-
SEX/DURATION :
-
female 5 day(s) after conception
-
TOXIC EFFECTS :
-
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
-
REFERENCE :
-
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 33,1094,1983
|
