Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Ergoline-8-beta-propionitrile, 6-methyl-alpha-(4-methyl-1-piperazinylc arbonyl)-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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74627-31-9

74627-31-9 structure

74627-31-9 structure

Name: Ergoline-8-beta-propionitrile, 6-methyl-alpha-(4-methyl-1-piperazinylc arbonyl)-
Chemical Name: 2-[[(6aR,9S)-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-yl]methyl]-3-(4-methylpiperazin-1-yl)-3-oxopropanenitrile
CAS Number: 74627-31-9
Molecular Formula: C₂₄H₃₁N₅O
Molecular Weight: 405.53600
Create Date: 2016-10-27 08:03:46
Modify Date: 2024-01-13 22:41:35

Name	2-[[(6aR,9S)-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-yl]methyl]-3-(4-methylpiperazin-1-yl)-3-oxopropanenitrile

Density	1.204g/cm3
Boiling Point	641.9ºC at 760 mmHg
Molecular Formula	C₂₄H₃₁N₅O
Molecular Weight	405.53600
Flash Point	342ºC
Exact Mass	405.25300
PSA	66.37000
LogP	2.24548
Index of Refraction	1.615

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KE6345210

CHEMICAL NAME :: Ergoline-8-beta-propionitrile, 6-methyl-alpha-(4-methyl-1-piperazinylcarbonyl)-

CAS REGISTRY NUMBER :: 74627-31-9

LAST UPDATED :: 199309

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C24-H31-N5-O

MOLECULAR WEIGHT :: 405.60

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Vascular - BP lowering not characterized in autonomic section

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 33,1094,1983 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 16 mg/kg

SEX/DURATION :: female 5 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 33,1094,1983