1503-53-3

• 常用中文名：2-乙酰氧基-5-溴苯甲酸
• 常用英文名：Benzoic acid,2-(acetyloxy)-5-bromo-
• CAS号：1503-53-3
• 分子式：C₉H₇BrO₄
• 分子量：259.05300
• 发布时间：2018-09-16 13:26:26
• 更新时间：2024-01-02 10:14:59

名称

• 中文名: 2-乙酰氧基-5-溴苯甲酸
• 英文名: 2-acetyloxy-5-bromobenzoic acid
• 中文别名: 5-溴水杨酸 乙酸酯
• 英文别名: 5-bromo-2-acetoxybenzoic acid; 5-Bromosalicylic acid acetate; 2-Acetoxy-5-brom-benzoesaeure; 5-Bromo-2-acetylsalicylic acid; 5-bromoaspirin; 5-Bromoacetylsalicylic acid; 2-Acetoxy-5-bromobenzoic acid; Sedasprin; Bromoaspirin; acetyl-5-bromosalicylic acid

物化性质

• 密度: 1.662g/cm3
• 沸点: 368.4ºC at 760mmHg
• 熔点: 60 °C
• 分子式: C₉H₇BrO₄
• 分子量: 259.05300
• 闪点: 176.6ºC
• 精确质量: 257.95300
• PSA: 63.60000
• LogP: 2.07260
• 蒸汽压: 4.46E-06mmHg at 25°C
• 折射率: 1.585
• 储存条件: 室温

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : VO1870000 CHEMICAL NAME : Salicylic acid, 5-bromo-, acetate CAS REGISTRY NUMBER : 1503-53-3 BEILSTEIN REFERENCE NO. : 2695058 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C9-H7-Br-O4 MOLECULAR WEIGHT : 259.07 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1130 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) REFERENCE : CRAAA7 Current Researches in Anesthesia and Analgesia. (Cleveland, OH) V.1-35, 1922-56. For publisher information, see AACRAT. Volume(issue)/page/year: 25,221,1946 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 650 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) REFERENCE : CRAAA7 Current Researches in Anesthesia and Analgesia. (Cleveland, OH) V.1-35, 1922-56. For publisher information, see AACRAT. Volume(issue)/page/year: 25,221,1946 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 16800 mg/kg/8W-C TOXIC EFFECTS : Musculoskeletal - other changes Related to Chronic Data - death REFERENCE : CRAAA7 Current Researches in Anesthesia and Analgesia. (Cleveland, OH) V.1-35, 1922-56. For publisher information, see AACRAT. Volume(issue)/page/year: 25,221,1946

安全

• 海关编码: 2918990090

合成路线

89-55-4 108-24-7 ~86% 1503-53-3

文献：Sharma, Horrick; Patil, Shivaputra; Sanchez, Tino W.; Neamati, Nouri; Schinazi, Raymond F.; Buolamwini, John K. Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 6 p. 2030 - 2045

89-55-4 ~87% 1503-53-3

文献：Kowa Co., Ltd. Patent: US6136848 A1, 2000 ;

89-55-4 75-36-5 ~96% 1503-53-3

文献：TRANSTECH PHARMA, INC. Patent: WO2004/14844 A2, 2004 ; Location in patent: Page 203 ; WO 2004/014844 A2

上下游产品

上游产品  3
89-55-4 108-24-7 75-36-5
下游产品  4
30779-63-6 7120-43-6 6329-74-4 5485-91-6

海关

海关编码	2918990090
中文概述	2918990090. 其他含其他附加含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%