2593-15-9

• 常用中文名：氯唑灵
• 常用英文名：etridiazole
• CAS号：2593-15-9
• 分子式：C₅H₅Cl₃N₂OS
• 分子量：247.530
• 相关类别： 分析化学 标准品 化妆品标准品
• 发布时间：2018-07-07 20:32:35
• 更新时间：2024-01-03 18:18:34
• 下载msds

名称

• 中文名: 土菌灵
• 英文名: etridiazole
• 中文别名: 5-乙氧基-3-三氯甲基-1,2,4-噻二唑; 氯唑灵
• 英文别名: Echlomezole; MFCD00071812; Banrot; 3-(trichloromethyl)-5-ethoxy-1,2,4-thiadiazole; 1,2,4-Thiadiazole, 5-ethoxy-3- (trichloromethyl)-; 1,2,4-Thiadiazole, 5-ethoxy-3-(trichloromethyl)-; etridiazole; Ethazol; Etcmtb; 5-ethoxy-3-trichloromethyl-[1,2,4]thiadiazole; 5-Ethoxy-3-trichloromethyl-1,2,4-thiadiazole,Ethazol; Truban; Ethyl 3-(trichloromethyl)-1,2,4-thiadiazol-5-yl ether; EINECS 219-991-8; 5-Ethoxy-3-(trichlorometyl)-1,2,4-thiadiazole; Terracoat; 5-Ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole; echlomezol; 5-ethoxy-3-trichloromethyl-1,2,4-thiaziazole; ethyl 3-trichloromethyl-1,2,4-thiadiazol-5-yl ether; T5NS DNJ CO2 EXGGG; Aaterra; Etridiazol

物化性质

• 密度: 1.6±0.1 g/cm3
• 沸点: 254.7±50.0 °C at 760 mmHg
• 熔点: 19.9°C
• 分子式: C₅H₅Cl₃N₂OS
• 分子量: 247.530
• 闪点: 107.8±30.1 °C
• 精确质量: 245.918823
• PSA: 63.25000
• LogP: 3.27
• 外观性状: Liquid
• 蒸汽压: 0.0±0.5 mmHg at 25°C
• 折射率: 1.565
• 储存条件:

  密封于0-6ºC阴凉干燥环境。

• 稳定性:

  如果遵照规格使用和储存则不会分解。

• 分子结构:

  1、 摩尔折射率：51.16

  2、 摩尔体积（m³/mol）：157.1

  3、 等张比容（90.2K）：419.1

  4、 表面张力（dyne/cm）：50.5

  5、 极化率（10^-24cm³）：20.28

• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:0

  3.氢键受体数量:4

  4.可旋转化学键数量:2

  5.互变异构体数量:无

  6.拓扑分子极性表面积63.2

  7.重原子数量:12

  8.表面电荷:0

  9.复杂度:154

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1. 性状：无可用

  2. 密度（g/mL,25/4℃）：无可用

  3. 相对蒸汽密度（g/mL,空气=1）：无可用

  4. 熔点（ºC）：无可用

  5. 沸点（ºC,常压）：无可用

  6. 沸点（ºC,5.2kPa）：无可用

  7. 折射率：无可用

  8. 闪点（ºC）：154.5

  9. 比旋光度（º）：无可用

  10. 自燃点或引燃温度（ºC）：无可用

  11. 蒸气压（kPa,25ºC）：无可用

  12. 饱和蒸气压（kPa,60ºC）：无可用

  13. 燃烧热（KJ/mol）：无可用

  14. 临界温度（ºC）：无可用

  15. 临界压力（KPa）：无可用

  16. 油水（辛醇/水）分配系数的对数值：无可用

  17. 爆炸上限（%,V/V）：无可用

  18. 爆炸下限（%,V/V）： 无可用

  19. 溶解性：无可用

MSDS

Section1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE Product identifiers Product name: Etridiazole CAS-No.: 2593-15-9 Relevant identified uses of the substance or mixture and uses advised against Identified uses: Laboratory chemicals, Manufacture of substances Section2. HAZARDS IDENTIFICATION Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP] Carcinogenicity (Category 2) Acute toxicity, Inhalation (Category 3) Acute toxicity, Dermal (Category 4) Acute toxicity, Oral (Category 4) Acute aquatic toxicity (Category 1) Chronic aquatic toxicity (Category 1) Classification according to EU Directives 67/548/EEC or 1999/45/EC Limited evidence of a carcinogenic effect. Toxic by inhalation. Harmful in contact with skin and if swallowed. Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Label elements Labelling according Regulation (EC) No 1272/2008 [CLP] Pictogram Signal wordDanger Hazard statement(s) H302Harmful if swallowed. H312Harmful in contact with skin. H331Toxic if inhaled. H351Suspected of causing cancer. H410Very toxic to aquatic life with long lasting effects. Precautionary statement(s) P261Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P273Avoid release to the environment. P280Wear protective gloves/ protective clothing. P311Call a POISON CENTER or doctor/ physician. P501Dispose of contents/ container to an approved waste disposal plant. Supplemental Hazardnone Statements According to European Directive 67/548/EEC as amended. Hazard symbol(s) R-phrase(s) R21/22Harmful in contact with skin and if swallowed. R23Toxic by inhalation. R40Limited evidence of a carcinogenic effect. R50/53Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. S-phrase(s) S36/37Wear suitable protective clothing and gloves. S38In case of insufficient ventilation, wear suitable respiratory equipment. S45In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). S60This material and its container must be disposed of as hazardous waste. S61Avoid release to the environment. Refer to special instructions/ Safety data sheets. Other hazards - none Section3. COMPOSITION/INFORMATION ON INGREDIENTS Substances Formula: C5H5Cl3N2OS Molecular Weight: 247,53 g/mol ComponentConcentration Etridiazole CAS-No.2593-15-9- EC-No.219-991-8 Index-No.613-133-00-X Section4. FIRST AID MEASURES Description of first aid measures General advice Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician. In case of eye contact Flush eyes with water as a precaution. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. Most important symptoms and effects, both acute and delayed Indication of any immediate medical attention and special treatment needed no data available Section5. FIREFIGHTING MEASURES Extinguishing media Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Special hazards arising from the substance or mixture Carbon oxides, nitrogen oxides (NOx), Hydrogen chloride gas, Sulphur oxides Nature of decomposition products not known. Carbon oxides, nitrogen oxides (NOx), Sulphur oxides, Hydrogen chloride gas Advice for firefighters Wear self contained breathing apparatus for fire fighting if necessary. Further information no data available Section6. ACCIDENTAL RELEASE MEASURES Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal. Reference to other sections For disposal see section 13. Section7. HANDLING AND STORAGE Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Specific end uses no data available Section8. EXPOSURE CONTROLS/PERSONAL PROTECTION Control parameters Components with workplace control parameters Exposure controls Appropriate engineering controls Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product. Personal protective equipment Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Section9. PHYSICAL AND CHEMICAL PROPERTIES Information on basic physical and chemical properties a) AppearanceForm: liquid Colour: light yellow b) Odourno data available c) Odour Thresholdno data available d) pHno data available e) Melting point/freezingno data available point f) Initial boiling point and 95 °C at 1 hPa boiling range g) Flash point154,5 °C - open cup h) Evaporation rateno data available i) Flammability (solid, gas) no data available j) Upper/lowerno data available flammability or explosive limits k) Vapour pressure0,015 hPa at 25 °C l) Vapour densityno data available m) Relative density1,503 g/cm3 at 25 °C n) Water solubilityslightly soluble o) Partition coefficient: n- log Pow: 3,37 octanol/water p) Autoignitionno data available temperature q) Decompositionno data available temperature r) Viscosityno data available s) Explosive propertiesno data available t) Oxidizing propertiesno data available Other safety information no data available Section10. STABILITY AND REACTIVITY Reactivity no data available Chemical stability no data available Possibility of hazardous reactions no data available Conditions to avoid no data available Incompatible materials Strong oxidizing agents Hazardous decomposition products Other decomposition products - no data available Section11. TOXICOLOGICAL INFORMATION Information on toxicological effects Acute toxicity LD50 Oral - rat - 1.077 mg/kg LC50 Inhalation - rat - 4 h - 5,7 mg/l LD50 Dermal - rabbit - 1.700 mg/kg Skin corrosion/irritation no data available Serious eye damage/eye irritation no data available Respiratory or skin sensitization no data available Germ cell mutagenicity no data available Carcinogenicity Limited evidence of carcinogenicity in animal studies IARC:No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. Reproductive toxicity no data available Specific target organ toxicity - single exposure no data available Specific target organ toxicity - repeated exposure no data available Aspiration hazard no data available Potential health effects Inhalation Toxic if inhaled. May cause respiratory tract irritation. IngestionHarmful if swallowed. Skin Harmful if absorbed through skin. May cause skin irritation. EyesMay cause eye irritation. Additional Information RTECS: XI3875000 Section12. ECOLOGICAL INFORMATION Toxicity Toxicity to fishLC50 - Oncorhynchus mykiss (rainbow trout) - 0,63 - 0,95 mg/l - 96,0 h Toxicity to daphnia and EC50 - Daphnia magna (Water flea) - 3,7 - 6,5 mg/l - 48 h other aquatic invertebrates Toxicity to algaeEC50 - Pseudokirchneriella subcapitata (green algae) - 0,003 - 0,019 mg/l - 5 d Persistence and degradability no data available Bioaccumulative potential no data available Mobility in soil no data available Results of PBT and vPvB assessment no data available Other adverse effects Very toxic to aquatic life. Section13. DISPOSAL CONSIDERATIONS Waste treatment methods Product Offer surplus and non-recyclable solutions to a licensed disposal company. Contaminated packaging Dispose of as unused product. Section14. TRANSPORT INFORMATION UN number ADR/RID: 3082IMDG: 3082IATA: 3082 UN proper shipping name ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S. (Etridiazole) IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S. (Etridiazole) IATA:Environmentally hazardous substance, liquid, n.o.s. (Etridiazole) Transport hazard class(es) ADR/RID: 9IMDG: 9IATA: 9 Packaging group ADR/RID: IIIIMDG: IIIIATA: III Environmental hazards ADR/RID: yesIMDG Marine pollutant: yesIATA: yes Special precautions for user Further information EHS-Mark required (ADR 2.2.9.1.10, IMDG code 2.10.3) for single packagings and combination packagings containing inner packagings with Dangerous Goods > 5L for liquids or > 5kg for solids. Section15. REGULATORY INFORMATION This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006. Safety, health and environmental regulations/legislation specific for the substance or mixture no data available Chemical Safety Assessment no data available Section16. OTHER INFORMATION Further information Copyright 2012 Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.

毒性和生态

毒理学数据: 1 。 试验方法：行政上的皮肤 摄入剂量： 2820年mg/kg/3W-I 测试对象：啮齿动物-兔 毒性类型： MutipleDose 毒性作用： 1.其他变化 2.改变白细胞（白血球）计数 3.慢性数据-死亡 2 。 试验方法：口服 摄入剂量： 1077毫克/千克 测试对象：啮齿动物-鼠 毒性类型：急性 毒性作用： 详细的毒副作用没有报告以外的其他致死剂量值 3 。 试验方法：口服 摄入剂量： 2毫克/千克 测试对象：啮齿动物-鼠 毒性类型：急性 毒性作用： 详细的毒副作用没有报告以外的其他致死剂量值 生态学数据: 该物质对环境可能有危害，对水体应给予特别注意。 CHEMICAL IDENTIFICATION RTECS NUMBER : XI3875000 CHEMICAL NAME : 1,2,4-Thiadiazole, 5-ethoxy-3-(trichloromethyl)- CAS REGISTRY NUMBER : 2593-15-9 LAST UPDATED : 199710 DATA ITEMS CITED : 15 MOLECULAR FORMULA : C5-H5-Cl3-N2-O-S MOLECULAR WEIGHT : 247.53 WISWESSER LINE NOTATION : T5NS DNJ CO2 EXGGG HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1077 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : >5000 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 779 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 1700 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 5687 mg/kg/13W-C TOXIC EFFECTS : Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 3640 mg/kg/13W-C TOXIC EFFECTS : Liver - changes in liver weight TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 18200 mg/kg/2Y-C TOXIC EFFECTS : Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 2820 mg/kg/3W-I TOXIC EFFECTS : Cardiac - other changes Blood - changes in leukocyte (WBC) count Related to Chronic Data - death MUTATION DATA TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 400 ug/plate REFERENCE : KHFKDF K'o Hsueh Fa Chan Yueh K'an. Progress in Sciences. (Kuo Chia K'o Hsueh Wei Yuan Hui, 2 Canton St., Taipei 107, Taiwan) V.1- 1973- Volume(issue)/page/year: 8,551,1980 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 1 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0716 No. of Facilities: 38 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 202 (estimated)

安全

• 符号: GHS06, GHS08, GHS09
• 信号词: Danger
• 危害声明: H302-H312-H331-H351-H410
• 警示性声明: P261-P273-P280-P311-P501
• 个人防护装备: Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
• 危害码 (欧洲): T: Toxic;N: Dangerous for the environment;
• 风险声明 (欧洲): R20/21/22;R23;R40;R50/53
• 安全声明 (欧洲): S38;S45;S60;S61;S36/S37
• 危险品运输编码: UN 2810
• RTECS号: XI3875000
• 海关编码: 2934999024

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海关

海关编码	2934999024
中文概述	HS:2934999024 代森硫,代森环,福吗啉 ,咯菌腈等〔包括稻瘟酯,烯酰吗啉,噻菌腈,土菌灵,恶霜灵,恶霉灵〕 增值税率:17.0% 退税率:9.0% 监管条件:S 最低关税:6.5% 普通关税:20.0%
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监管条件	S.进出口农药登记证明
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