13292-45-0

• 常用中文名：N-去甲利福平
• 常用英文名：Rifamycin,3-[(1-piperazinylimino)methyl]-
• CAS号：13292-45-0
• 分子式：C₄₂H₅₆N₄O₁₂
• 分子量：808.91400
• 相关类别： 原料药 抗生素类药物 利福霉素类药
• 发布时间：2018-08-26 10:32:12
• 更新时间：2024-04-02 12:28:47

名称

• 中文名: N-去甲利福平
• 英文名: N-Demethyl Rifampin
• 英文别名: 4-N-Demethylrifampicin; rifaldehyde piperazin-1-ylhydrazone; Rifampicin AF/AP; 3-(piperazin-1-ylimino-methyl)-rifamycin; N-Demethylrifampin; AF/AP; N-Demethylrifampicin; Rifampicin AF/A; 3-(piperidinyliminomethyl)rifamycin SV; Demethylrifampicin

物化性质

• 密度: 1.35g/cm3
• 分子式: C₄₂H₅₆N₄O₁₂
• 分子量: 808.91400
• 精确质量: 808.38900
• PSA: 228.94000
• LogP: 4.39790
• 折射率: 1.631

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : KD1923000 CHEMICAL NAME : 2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b) furan-1,11(2H)-dione, 5,6,9,17,19,21- hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl -8-(N-1-piperazinylfo rmimidoyl)-, 21- acetate CAS REGISTRY NUMBER : 13292-45-0 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C42-H56-N4-O12 MOLECULAR WEIGHT : 809.02 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 695 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value MUTATION DATA TYPE OF TEST : DNA inhibition TEST SYSTEM : Human Lymphocyte DOSE/DURATION : 100 mg/L REFERENCE : BBRCA9 Biochemical and Biophysical Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 60,96,1974