CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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UR6040000
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CHEMICAL NAME :
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Pyridazine, 3-hydrazino-6-((2-hydroxypropyl)methylamino)-, dihydrochloride
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CAS REGISTRY NUMBER :
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56393-22-7
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LAST UPDATED :
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199112
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DATA ITEMS CITED :
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4
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MOLECULAR FORMULA :
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C8-H15-N5-O.2Cl-H
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MOLECULAR WEIGHT :
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270.20
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WISWESSER LINE NOTATION :
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T6NNJ CMZ F1M1YQ1 &GH 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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1230 mg/kg
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TOXIC EFFECTS :
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Cardiac - pulse rate increase, without fall in BP Vascular - BP lowering not characterized in autonomic section
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REFERENCE :
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PLRCAT Pharmacological Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1969- Volume(issue)/page/year: 8,295,1976
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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355 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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PLRCAT Pharmacological Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1969- Volume(issue)/page/year: 8,295,1976
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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1170 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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PLRCAT Pharmacological Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1969- Volume(issue)/page/year: 8,295,1976
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TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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357 mg/kg
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TOXIC EFFECTS :
-
Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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PLRCAT Pharmacological Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1969- Volume(issue)/page/year: 8,295,1976
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