566-19-8

• 常用中文名：7-酮基去氢表雄酮
• 常用英文名：7-Keto-dehydroepiandrosterone
• CAS号：566-19-8
• 分子式：C₁₉H₂₆O₃
• 分子量：302.408
• 相关类别： 天然产物 甾体化合物
• 发布时间：2018-03-11 08:00:00
• 更新时间：2024-01-02 11:43:22
• 用作医药中间体

名称

• 中文名: 7-酮基去氢表雄酮
• 英文名: 7-Keto Dehydro Epiandrosterone
• 中文别名: 7-酮基-去氢表雄酮
• 英文别名: 7-Keto-dehydroepiandrosterone; MFCD00198500; 3-Hydroxy-10,13-dimethyl-1,3,4,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-7,17-dione; Androst-5-ene-7,17-dione, 3-hydroxy-, (3β)-; (3β)-3-Hydroxyandrost-5-ene-7,17-dione; 3β-Hydroxyandrost-5-ene-7,17-dione

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 477.1±45.0 °C at 760 mmHg
• 熔点: 240.0-244.0ºC
• 分子式: C₁₉H₂₆O₃
• 分子量: 302.408
• 闪点: 256.5±25.2 °C
• 精确质量: 302.188202
• PSA: 54.37000
• LogP: 1.63
• 外观性状: 白色粉末
• 蒸汽压: 0.0±2.7 mmHg at 25°C
• 折射率: 1.569
• 储存条件: 室温

MSDS

Section 1. Chemical Product and Company Identification Dehydroepiandrosterone, 7-Keto Common Name/ Trade Name Dehydroepiandrosterone, 7-Keto Section 4. First Aid Measures Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least Eye Contact 15 minutes. Get medical attention if irritation occurs. Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Skin Contact Serious Skin ContactNot available. InhalationIf inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention. Not available. Serious Inhalation Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an Ingestion unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband. Not available. Serious Ingestion Section 5. Fire and Explosion Data Flammability of the Product May be combustible at high temperature. Auto-Ignition Temperature Not available. Not available. Flash Points Not available. Flammable Limits These products are carbon oxides (CO, CO2). Products of Combustion Fire Hazards in Presence of Slightly flammable to flammable in presence of heat. Various Substances Risks of explosion of the product in presence of mechanical impact: Not available. Explosion Hazards in Risks of explosion of the product in presence of static discharge: Not available. Presence of Various Substances SMALL FIRE: Use DRY chemical powder. Fire Fighting Media LARGE FIRE: Use water spray, fog or foam. Do not use water jet. and Instructions Material in powder form, capable of creating a dust explosion. As with most organic solids, fire is possible at elevated Special Remarks on temperatures Fire Hazards Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust Special Remarks on explosion hazard. Explosion Hazards Section 6. Accidental Release Measures Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading Small Spill water on the contaminated surface and dispose of according to local and regional authority requirements. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on Large Spill the contaminated surface and allow to evacuate through the sanitary system. Dehydroepiandrosterone, 7-Keto Section 7. Handling and Storage Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not Precautions breathe dust. Keep away from incompatibles such as oxidizing agents. Keep container tightly closed. Keep container in a cool, well-ventilated area. Storage Section 8. Exposure Controls/Personal Protection Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below Engineering Controls recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Personal ProtectionSafety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Personal Protection in Case Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE of a Large Spill handling this product. Exposure LimitsNot available. Section 9. Physical and Chemical Properties Solid. (Powdered solid.)Not available. Physical state andO dor appearance Not available. Taste 302.41 g/mole Molecular Weight White. Off-white. Color Not available. pH (1% soln/water) Not available. Boiling Point 242°C (467.6°F) -244 C. Melting Point Not available. Critical Temperature Not available. Specific Gravity Not applicable. Vapor Pressure Not available. Vapor Density Not available. Volatility Not available. Odor Threshold Not available. Water/Oil Dist. Coeff. Not available. Ionicity (in Water) Not available. Dispersion Properties Not available. Solubility Section 10. Stability and Reactivity Data The product is stable. Stability Not available. Instability Temperature Conditions of Instability Excess heat, incompatible materials, dust generation. Incompatibility with various Reactive with oxidizing agents. substances Not available. Corrosivity Dehydroepiandrosterone, 7-Keto Not available. Special Remarks on Reactivity Not available. Special Remarks on Corrosivity Will not occur. Polymerization Section 11. Toxicological Information Inhalation. Ingestion. Routes of Entry Toxicity to AnimalsLD50: Not available. LC50: Not available. Chronic Effects on Humans Not available. Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation. Other Toxic Effects on Humans Not available. Special Remarks on Toxicity to Animals May cause adverse reproductive effects and birth defects (teratogenic). Special Remarks on Chronic Effects on Humans May affect genetic material (mutagenic). May cause cancer Special Remarks on otherPotential Health Effects: Skin: May cause skin irritation. Toxic Effects on Humans Eyes: Dust may cause eye irritation. Inhalation: Dust may cause respiratory tract irritation. Ingestion: May affect the liver, spleen, cardiovascular system(cardiac arrhythmias). Medical Conditions Aggravated by Exposure: Because it is a precusor of testosterone and estrogen, people with cancer (such as breast, ovarian, and testicular cancer) should avoid it.; if currently being treated with the following medications: AZT, Barbiturates, Cisplatin, Steroids, Estrogen. Section 12. Ecological Information Not available. Ecotoxicity Not available. BOD5 and COD Products of Biodegradation Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise. The product itself and its products of degradation are not toxic. Toxicity of the Products of Biodegradation Not available. Special Remarks on the Products of Biodegradation Section 13. Disposal Considerations Waste must be disposed of in accordance with federal, state and local environmental control Waste Disposal regulations. Dehydroepiandrosterone, 7-Keto Section 14. Transport Information DO T Cl assi fi cati onNot a DOT controlled material (United States). Not applicable. Identification Not applicable. Special Provisions for Transport DO T (Pi ctograms) Section 15. Other Regulatory Information and Pictograms California prop. 65: This product contains the following ingredients for which the State of California has found to Federal and State cause cancer, birth defects or other reproductive harm, which would require a warning under the statute: Regulations Dehydroepiandrosterone, 7-Keto California prop. 65: This product contains the following ingredients for which the State of California has found to cause reproductive harm (female) which would require a warning under the statute: Dehydroepiandrosterone, 7-Keto California prop. 65: This product contains the following ingredients for which the State of California has found to cause reproductive harm (male) which would require a warning under the statute: Dehydroepiandrosterone, 7-Keto California prop. 65: This product contains the following ingredients for which the State of California has found to California cause cancer which would require a warning under the statute: No products were found. Proposition 65 Warnings California prop. 65: This product contains the following ingredients for which the State of California has found to cause birth defects which would require a warning under the statute: No products were found. Not available. Other Regulations WHMIS (Canada) CLASS D-2A: Material causing other toxic effects (VERY TOXIC). Other Classifications This product is not classified according Not applicable. DSCL (EEC) to the EU regulations. Health Hazard HMIS (U.S.A.)1 National Fire Protection 1 Flammability 1 Association (U.S.A.) Fire Hazard 1 0 Reactivity Health Reactivity 0 Specific hazard Personal Protection E WHMIS (Canada) (Pictograms) DSCL (Europe) (Pictograms) TDG(Canada) (Pictograms) Dehydroepiandrosterone, 7-Keto ADR (Europe) (Pictograms) Protective Equipment Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xn
• 海关编码: 2937290090

合成路线

上下游产品

上游产品  7
166173-97-3 53-43-0 2487-48-1 7745-40-6
853-23-6 1449-61-2 1189-85-1
下游产品  4
1420-49-1 2697-85-0 2226-65-5 1449-61-2

海关

海关编码	2937290090