157665-46-8

• 常用中文名：2-氟-4-硝基苯甲酸叔丁酯
• 常用英文名：tert-butyl 2-fluoro-4-nitrobenzoate
• CAS号：157665-46-8
• 分子式：C₁₁H₁₂FNO₄
• 分子量：241.21600
• 发布时间：2018-04-22 08:00:00
• 更新时间：2024-01-10 10:34:37

名称

• 中文名: 2-氟-4-硝基苯甲酸叔丁酯
• 英文名: tert-butyl 2-fluoro-4-nitrobenzoate
• 英文别名: AB1289; tert-butyl 2-fluoro-4-nitro-benzoate

物化性质

• 分子式: C₁₁H₁₂FNO₄
• 分子量: 241.21600
• 精确质量: 241.07500
• PSA: 72.12000
• LogP: 3.21240
• 储存条件: 室温

合成路线

24424-99-5 403-24-7 ~98% 157665-46-8

文献：DR. REDDY'S LABORATORIES LIMITED; DR. REDDY'S LABORATORIES, INC. Patent: WO2008/143649 A2, 2008 ; Location in patent: Page/Page column 49-50 ;

403-24-7 ~% 157665-46-8

文献：Pharmacia and Upjohn Company Patent: US6441005 B1, 2002 ;

1427-07-2 ~% 157665-46-8

文献：Gordeev, Mikhail F.; Hackbarth, Corinne; Barbachyn, Michael R.; Banitt, Lee S.; Gage, James R.; Luehr, Gary W.; Gomez, Marcela; Trias, Joaquim; Morin, Sara E.; Zurenko, Gary E.; Parker, Christian N.; Evans, Jonathan M.; White, Richard J.; Patel, Dinesh V. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 23 p. 4213 - 4216

403-23-6 75-65-0 ~% 157665-46-8

文献：Springer; Niculescu-Duvaz; Pedley Journal of Medicinal Chemistry, 1994 , vol. 37, # 15 p. 2361 - 2370

403-24-7 75-65-0 ~% 157665-46-8

文献：Marsham; Jackman; Barker; Boyle; Pegg; Wardleworth; Kimbell; O'Connor; Calvert; Hughes Journal of Medicinal Chemistry, 1995 , vol. 38, # 6 p. 994 - 1004

403-23-6 1907-33-1 ~% 157665-46-8

文献：Gordeev, Mikhail F.; Hackbarth, Corinne; Barbachyn, Michael R.; Banitt, Lee S.; Gage, James R.; Luehr, Gary W.; Gomez, Marcela; Trias, Joaquim; Morin, Sara E.; Zurenko, Gary E.; Parker, Christian N.; Evans, Jonathan M.; White, Richard J.; Patel, Dinesh V. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 23 p. 4213 - 4216