425378-70-7

• 常用中文名：5-氨基-2-氟联苯-2-甲腈
• 常用英文名：2-(5-amino-2-fluorophenyl)benzonitrile
• CAS号：425378-70-7
• 分子式：C₁₃H₉FN₂
• 分子量：212.22200
• 发布时间：2018-03-02 08:00:00
• 更新时间：2024-01-10 10:52:06

名称

• 中文名: 5-氨基-2-氟联苯-2-甲腈
• 英文名: 2-(5-amino-2-fluorophenyl)benzonitrile
• 英文别名: [1,1'-Biphenyl]-2-carbonitrile,5'-amino-2'-fluoro; 5'-AMINO-2'-FLUOROBIPHENYL-2-CARBONITRILE

物化性质

• 分子式: C₁₃H₉FN₂
• 分子量: 212.22200
• 精确质量: 212.07500
• PSA: 49.81000
• LogP: 3.52778

合成路线

425378-69-4 ~72% 425378-70-7

文献：MERCK SHARP and DOHME LIMITED Patent: WO2003/99816 A1, 2003 ; Location in patent: Page 49-50 ; WO 03/099816 A1

425378-68-3 ~% 425378-70-7

文献：Goodacre, Simon C.; Street, Leslie J.; Hallett, David J.; Crawforth, James M.; Kelly, Sarah; Owens, Andrew P.; Blackaby, Wesley P.; Lewis, Richard T.; Stanley, Joanna; Smith, Alison J.; Ferris, Pushpinder; Sohal, Bindi; Cook, Susan M.; Pike, Andrew; Brown, Nicola; Wafford, Keith A.; Marshall, George; Castro, Jose L.; Atack, John R. Journal of Medicinal Chemistry, 2006 , vol. 49, # 1 p. 35 - 38

2042-37-7 ~% 425378-70-7

文献：Goodacre, Simon C.; Street, Leslie J.; Hallett, David J.; Crawforth, James M.; Kelly, Sarah; Owens, Andrew P.; Blackaby, Wesley P.; Lewis, Richard T.; Stanley, Joanna; Smith, Alison J.; Ferris, Pushpinder; Sohal, Bindi; Cook, Susan M.; Pike, Andrew; Brown, Nicola; Wafford, Keith A.; Marshall, George; Castro, Jose L.; Atack, John R. Journal of Medicinal Chemistry, 2006 , vol. 49, # 1 p. 35 - 38

701-45-1 ~% 425378-70-7

文献：Goodacre, Simon C.; Street, Leslie J.; Hallett, David J.; Crawforth, James M.; Kelly, Sarah; Owens, Andrew P.; Blackaby, Wesley P.; Lewis, Richard T.; Stanley, Joanna; Smith, Alison J.; Ferris, Pushpinder; Sohal, Bindi; Cook, Susan M.; Pike, Andrew; Brown, Nicola; Wafford, Keith A.; Marshall, George; Castro, Jose L.; Atack, John R. Journal of Medicinal Chemistry, 2006 , vol. 49, # 1 p. 35 - 38

上下游产品

上游产品  3
425378-68-3 2042-37-7 701-45-1
下游产品  1
425378-71-8