51307-43-8

• 常用中文名：2-氨基-4-羟甲基噻唑
• 常用英文名：(2-Aminothiazol-4-yl)methanol
• CAS号：51307-43-8
• 分子式：C₄H₆N₂OS
• 分子量：130.168
• 发布时间：2018-07-08 09:51:40
• 更新时间：2024-01-03 16:11:49

名称

• 中文名: 2-氨基-4-羟甲基噻唑
• 英文名: (2-Aminothiazol-4-yl)methanol
• 中文别名: (2-氨基-1,3-噻唑-4-基)甲醇; 2-氨基噻唑-4-甲醇
• 英文别名: 2-Amino-4-hydroxymethylthiazole; (2-Amino-1,3-thiazol-4-yl)methanol; 4-Thiazolemethanol, 2-amino-

物化性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 340.7±17.0 °C at 760 mmHg
• 分子式: C₄H₆N₂OS
• 分子量: 130.168
• 闪点: 159.9±20.9 °C
• 精确质量: 130.020081
• PSA: 87.38000
• LogP: -0.80
• 外观性状: 淡黄色油状
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.682
• 储存条件: 2-8°C

MSDS

Material Safety Data Sheet Section1. Identification of the substance Product Name: (2-Aminothiazol-4-yl)methanol Synonyms: Section2. Hazards identification Harmful by inhalation, in contact with skin, and if swallowed. Section3. Composition/information on ingredients. Ingredient name:(2-Aminothiazol-4-yl)methanol CAS number:51307-43-8 Section4. First aid measures Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing contaminated clothing and shoes. If irritation persists, seek medical attention. Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical attention. Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention. Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention. Section5. Fire fighting measures In the event of a fire involving this material, alone or in combination with other materials, use dry powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus should be worn. Section6. Accidental release measures Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national standards. Respiratory precaution:Wear approved mask/respirator Hand precaution:Wear suitable gloves/gauntlets Skin protection:Wear suitable protective clothing Eye protection:Wear suitable eye protection Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container for disposal. See section 12. Environmental precautions: Do not allow material to enter drains or water courses. Section7. Handling and storage Handling:This product should be handled only by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals, who should take into account the fire, health and chemical hazard data given on this sheet. Store in closed vessels, refrigerated. Storage: Section8. Exposure Controls / Personal protection Engineering Controls: Use only in a chemical fume hood. Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles. General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse. Section9. Physical and chemical properties Appearance:Not specified Boiling point:No data No data Melting point: Flash point:No data Density:No data Molecular formula:C4H6N2OS Molecular weight:130.2 Section10. Stability and reactivity Conditions to avoid: Heat, flames and sparks. Materials to avoid: Oxidizing agents. Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, sulfur oxides. Section11. Toxicological information No data. Section12. Ecological information No data. Section13. Disposal consideration Arrange disposal as special waste, by licensed disposal company, in consultation with local waste disposal authority, in accordance with national and regional regulations. Section14. Transportation information Non-harzardous for air and ground transportation. Section15. Regulatory information No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302, or have known CAS numbers that exceed the threshold reporting levels established by SARA Title III, Section 313. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xi
• 海关编码: 2934100090

合成路线

38987-72-3 17356-08-0 ~80% 51307-43-8

文献：AMGEN INC. Patent: US2007/173506 A1, 2007 ; Location in patent: Page/Page column 34 ;

1192-50-3 17356-08-0 ~% 51307-43-8

文献：Sprague et al. Journal of the American Chemical Society, 1946 , vol. 68, p. 2155,2158

89713-01-9 ~% 51307-43-8

文献：Albers,H.; Mohler,W. Chemische Berichte, 1963 , vol. 96, p. 357 - 362

5398-36-7 ~% 51307-43-8

文献：IRM LLC; CHE, Jianwei; DING, Qiang; HE, Xiaohui; LIU, Hong; LIU, Yahua; MICHELLYS, Pierre-Yves; OKRAM, Barun; WU, Xu; YANG, Kunyong; ZHU, Xuefeng Patent: WO2011/14795 A2, 2011 ; Location in patent: Page/Page column 92 ; WO 2011/014795 A2

59608-97-8 ~% 51307-43-8

文献：FUJISAWA PHARMACEUTICAL CO., LTD. Patent: EP224919 B1, 1991 ;

上下游产品

上游产品  4
5398-36-7 59608-97-8 38987-72-3 1192-50-3
下游产品  0

海关

海关编码	2934100090
中文概述	2934100090. 结构上含有一个非稠合噻唑环的化合物(不论是否氢化). 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%