306934-76-9

• 常用中文名：5-甲基-6-苯基噻吩[2,3-D]嘧啶-4-醇
• 常用英文名：5-methyl-6-phenylthieno[2,3-d]pyrimidin-4-ol
• CAS号：306934-76-9
• 分子式：C₁₃H₁₀N₂OS
• 分子量：242.29600
• 相关类别： 医药中间体 杂环化合物 嘧啶类化合物 苯基嘧啶
• 发布时间：2019-01-21 09:54:21
• 更新时间：2024-01-14 06:43:05

名称

• 中文名: 5-甲基-6-苯基噻吩[2,3-D]嘧啶-4-醇
• 英文名: 5-methyl-6-phenyl-3H-thieno[2,3-d]pyrimidin-4-one
• 中文别名: 5-甲基-6-苯基噻吩并[2,3-D]嘧啶-4-醇
• 英文别名: 5-Methyl-6-phenylthieno[2,3-d]pyrimidin-4(3H)-one; HMS542I10; 5-methyl-6-phenylthieno[2,3-d]pyrimidin-4-ol; 5-methyl-6-phenyl-3-hydrothiopheno[2,3-d]pyrimidin-4-one

物化性质

• 密度: 1.37g/cm3
• 沸点: 484.8ºC at 760mmHg
• 熔点: 247-249ºC
• 分子式: C₁₃H₁₀N₂OS
• 分子量: 242.29600
• 闪点: 247ºC
• 精确质量: 242.05100
• PSA: 74.25000
• LogP: 3.37230
• 折射率: 1.714

MSDS

Name: 5-Methyl-6-phenylthieno[2 3-d]pyrimidin-4-ol 97% Material Safety Data Sheet Synonym: 4-Hydroxy-5-methyl-6-phenylthienol[2,3-d]pyrimidin CAS: 306934-76-9 Section 1 - Chemical Product MSDS Name:5-Methyl-6-phenylthieno[2 3-d]pyrimidin-4-ol 97% Material Safety Data Sheet Synonym:4-Hydroxy-5-methyl-6-phenylthienol[2,3-d]pyrimidin Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 306934-76-9 5-Methyl-6-phenylthieno[2,3-d]pyrimidi 97% unlisted Hazard Symbols: XI Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 306934-76-9: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: off-white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 247 - 249 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C13H10N2OS Molecular Weight: 242 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 306934-76-9 unlisted. LD50/LC50: Not available. Carcinogenicity: 5-Methyl-6-phenylthieno[2,3-d]pyrimidin-4-ol - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 306934-76-9: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 306934-76-9 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 306934-76-9 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xi: Irritant;
• 海关编码: 2934999090

合成路线

4815-39-8 141-53-7 ~60% 306934-76-9

文献：Ho, Jonathan Z.; Van Arsdale, Kyle R.; Braun, Matthew P. Helvetica Chimica Acta, 2008 , vol. 91, # 5 p. 958 - 963

4815-39-8 122-51-0 ~85% 306934-76-9

文献：Briel; Rybak; Kronbach; Unverferth Pharmazie, 2008 , vol. 63, # 11 p. 823 - 826

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%