50847-92-2

• 常用中文名：2,2-DIMETHYL-3-THIOMORPHOLINONE
• 常用英文名：2,2-DIMETHYL-3-THIOMORPHOLINONE
• CAS号：50847-92-2
• 分子式：C₆H₁₁NOS
• 分子量：145.22300
• 发布时间：2016-10-22 07:59:03
• 更新时间：2024-01-02 11:45:21

名称

• 英文名: 2,2-dimethylthiomorpholin-3-one
• 英文别名: 2,2-Dimethyl-3-thiomorpholinone; 3-Oxo-2.2-dimethyl-thiomorpholin; 2.2-Dimethyl-3-oxo-thiomorpholin; 3-Thiomorpholinone,2,2-dimethyl; 2,2-Dimethyl-3-thiomorpholone; 2,2-dimethyl-thiomorpholin-3-one; 2,2-Dimethyl-thiomorpholin-3-on; 2,2-dimethyl-3-oxothiomorpholine

物化性质

• 分子式: C₆H₁₁NOS
• 分子量: 145.22300
• 精确质量: 145.05600
• PSA: 54.40000
• LogP: 0.95680

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : XM3064000 CHEMICAL NAME : 3-Thiomorpholinone, 2,2-dimethyl- CAS REGISTRY NUMBER : 50847-92-2 BEILSTEIN REFERENCE NO. : 0112495 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C6-H11-N-O-S MOLECULAR WEIGHT : 145.24 WISWESSER LINE NOTATION : T6MV DSTJ C1 C1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3423 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 6,136,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490

合成路线

600-00-0 60-23-1 ~% 50847-92-2

文献：NOVARTIS AG; IRM LLC; CHEN, Bei; FAIRHURST, Robin, Alec; FLOERSHEIMER, Andreas; FURET, Pascal; GUAGNANO, Vito; JIANG, Songchun; LU, Wenshuo; MARSILJE, Thomas, H.; MCCARTHY, Clive; MICHELLYS, Pierre-Yves; STAUFFER, Frederic; STUTZ, Stefan; VAUPEL, Andrea Patent: WO2011/29915 A1, 2011 ; Location in patent: Page/Page column 71-72 ; WO 2011/029915 A1

151-56-4 33441-50-8 ~% 50847-92-2

文献：Lehr,H. et al. Journal of Medicinal Chemistry, 1963 , vol. 6, p. 136 - 141 Full Text View citing articles Show Details Hoffmann-La Roche Patent: US2755278 , 1954 ;

600-00-0 ~% 50847-92-2

文献：Hoffmann-La Roche Patent: US2755278 , 1954 ;