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13292-43-8

13292-43-8结构式
13292-43-8结构式
  • 常用中文名:NCI 143-447
  • 常用英文名:NCI 143-447
  • CAS号:13292-43-8
  • 分子式:C42H55N3O13
  • 分子量:809.89800
  • 发布时间:2017-05-18 21:49:52
  • 更新时间:2024-09-14 08:56:42

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英文名 3-<(1'-morpholinyl)iminomethyl>-rifamycin SV
英文别名 rifaldehyde morpholin-4-ylimine
密度 1.36g/cm3
分子式 C42H55N3O13
分子量 809.89800
精确质量 809.37300
PSA 226.14000
LogP 4.49610
折射率 1.626

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KD1920675
CHEMICAL NAME :
2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b) furan-1,11(2H)-dione, 5,6,9,17,19,21- hexahydroxy-2,4,12,16,18,20,22-heptamethyl-23-methoxy -8-(N-morpholinoformi midoyl)-, 21-acetate
CAS REGISTRY NUMBER :
13292-43-8
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C42-H55-N3-O13
MOLECULAR WEIGHT :
810.00

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 12,155,1967
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
510 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
38KLAC "Structure-Activity Relationship among the Semisynthetic Antibiotics," Perlman, D., ed., New York, Academic Press, 1977 Volume(issue)/page/year: -,531,1977

~38%

13292-43-8结构式

13292-43-8

文献:Bartolucci; Cellai; Di Filippo; Segre; Brufani; Filocamo; Bianco; Guiso; Brizzi; Benedetto; Di Caro; Elia Farmaco, 1992 , vol. 47, # 11 p. 1367 - 1383
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